[HTML][HTML] Biological age estimation using circulating blood biomarkers

J Bortz, A Guariglia, L Klaric, D Tang, P Ward… - Communications …, 2023 - nature.com
Biological age captures physiological deterioration better than chronological age and is
amenable to interventions. Blood-based biomarkers have been identified as suitable …

[HTML][HTML] An interpretable machine learning model of biological age

TR Wood, C Kelly, M Roberts, B Walsh - F1000Research, 2019 - f1000research.com
Background: Assessments of biological (rather than chronological) age derived from patient
biochemical data have been shown to strongly predict both all-cause and disease-specific …

[HTML][HTML] Prediction of chronological and biological age from laboratory data

L Sagers, L Melas-Kyriazi, CJ Patel… - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Aging has pronounced effects on blood laboratory biomarkers used in the clinic. Prior
studies have largely investigated one biomarker or population at a time, limiting a …

A biomarker-based biological age in UK Biobank: composition and prediction of mortality and hospital admissions

MS Chan, M Arnold, A Offer, I Hammami… - The Journals of …, 2021 - academic.oup.com
Background Chronological age is the strongest risk factor for most chronic diseases.
Developing a biomarker-based age and understanding its most important contributing …

[HTML][HTML] Using blood test parameters to define biological age among older adults: association with morbidity and mortality independent of chronological age validated …

J Drewelies, G Hueluer, S Duezel, VM Vetter… - Geroscience, 2022 - Springer
Biomarkers defining biological age are typically laborious or expensive to assess. Instead, in
the current study, we identified parameters based on standard laboratory blood tests across …

[HTML][HTML] Machine learning approaches for the estimation of biological aging: the road ahead for population studies

A Gialluisi, A Di Castelnuovo, MB Donati… - Frontiers in …, 2019 - frontiersin.org
In recent years, different machine learning algorithms have been developed for the
estimation of Biological Age (BA), defined as the hypothetical underlying age of an …

[HTML][HTML] The challenges of estimating biological age

A Moskalev - Elife, 2020 - elifesciences.org
Mortality: The challenges of estimating biological age | eLife Skip to Content eLife logo eLife
home page Menu Home Magazine Community About Search Alerts Submit your research …

[HTML][HTML] Biomarkers selection and mathematical modeling in biological age estimation

SEC Bafei, C Shen - npj Aging, 2023 - nature.com
Biological age (BA) is important for clinical monitoring and preventing aging-related
disorders and disabilities. Clinical and/or cellular biomarkers are measured and integrated …

[HTML][HTML] Biological age predictors: the status quo and future trends

VV Erema, AY Yakovchik, DA Kashtanova… - International Journal of …, 2022 - mdpi.com
There is no single universal biomarker yet to estimate overall health status and longevity
prospects. Moreover, a consensual approach to the very concept of aging and the means of …

Multi-omic biological age estimation and its correlation with wellness and disease phenotypes: a longitudinal study of 3,558 individuals

JC Earls, N Rappaport, L Heath… - The Journals of …, 2019 - academic.oup.com
Biological age (BA), derived from molecular and physiological measurements, has been
proposed to better predict mortality and disease than chronological age (CA). In the present …