Chromogranin A plasma levels predict mortality in COVID-19

R De Lorenzo, C Sciorati, GA Ramirez, B Colombo… - PloS One, 2022 - journals.plos.org
Background Chromogranin A (CgA) and its fragment vasostatin I (VS-I) are secreted in the
blood by endocrine/neuroendocrine cells and regulate stress responses. Their involvement …

Assessment of plasma Catestatin in COVID-19 reveals a hitherto unknown inflammatory activity with impact on morbidity-mortality

F Schneider, P Le Borgne, JE Herbrecht… - Frontiers in …, 2022 - frontiersin.org
Introduction Neuroendocrine cells release Catestatin (CST) from Chromogranin A (CgA) to
regulate stress responses. As regards COVID-19 patients (COVID+) requiring oxygen …

Serum concentration of chromogranin A at admission: an early biomarker of severity in critically ill patients

D Zhang, T Lavaux, R Sapin, T Lavigne… - Annals of …, 2009 - Taylor & Francis
Background. Chromogranin A (CGA), a stress marker released with catecholamines by the
adrenal medulla, has never been associated with acute inflammation in critically ill patients …

Prognostic value of chromogranin A at admission in critically ill patients: a cohort study in a medical intensive care unit

D Zhang, T Lavaux, AC Voegeli, T Lavigne… - Clinical …, 2008 - academic.oup.com
Background: Risk assessments of patients should be based on objective variables, such as
biological markers that can be measured routinely. The acute response to stress causes the …

Preanalytical factors of importance for measurement of Chromogranin A

L Pedersen, M Nybo - Clinica Chimica Acta, 2014 - Elsevier
Background Studies indicate that fasting and diurnal variation can influence serum
Chromogranin A (CgA) concentrations and furthermore, stability of the CgA molecule has …

Role of cystatin C and calprotectin as potential early prognostic biomarkers in COVID-19 patients admitted to a dedicated COVID care facility

T Kumar, D Bhushan, S Kumar, K Jha… - Journal of Family …, 2022 - journals.lww.com
Background: The COVID-19 pandemic has claimed millions of lives. A tool for early
prediction of severity and mortality risk is desirable for better utilization of health care …

Vasostatin-I, a chromogranin A-derived peptide, in non-selected critically ill patients: distribution, kinetics, and prognostic significance

F Schneider, C Bach, H Chung, L Crippa… - Intensive care …, 2012 - Springer
Abstract Purpose Chromogranin A (CGA) is released in the plasma during life-threatening
illnesses. Its N-terminal 1–76 peptide, vasostatin-I (VS-I), has never been assessed in …

Development of an immunoassay for the derived-peptide of chromogranin A, vasostatin-I (1-76): assessment of severity in patients with sepsis

H Chung, A Corti, L Crippa, F Schneider… - Biomarkers, 2012 - Taylor & Francis
Context: Proteolytic fragments of chromogranin A (CgA) including the CgA 1-76 fragment
(called vasostatin-I [VS-I]) could be a useful biomarker of sepsis, but there is no available …

Serum cystatin C and coronavirus disease 2019: a potential inflammatory biomarker in predicting critical illness and mortality for adult patients

D Chen, W Sun, J Li, B Wei, W Liu… - Mediators of …, 2020 - Wiley Online Library
This study aimed at determining the relationship between baseline cystatin C levels and
coronavirus disease 2019 (COVID‐19) and investigating the potential prognostic value of …

Longitudinal profiles of plasma gelsolin, cytokines and antibody expression predict COVID-19 severity and hospitalization outcomes

M Asare-Werehene, M McGuinty, A Vranjkovic… - Frontiers in …, 2022 - frontiersin.org
Background Prognostic markers for COVID-19 disease outcome are currently lacking.
Plasma gelsolin (pGSN) is an actin-binding protein and an innate immune marker involved …