Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability

D Forte, RM Pellegrino, S Trabanelli, T Tonetti… - Frontiers in …, 2023 - frontiersin.org
Introduction Extracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers
for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 …

[PDF][PDF] Serum‐derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID‐19 patients

T Tertel, S Tomić, J Đokić, D Radojević… - Journal of …, 2022 - Wiley Online Library
COVID‐19 is characterized by a wide spectrum of disease severity, whose indicators and
underlying mechanisms need to be identified. The role of extracellular vesicles (EVs) in …

Circulating platelet-derived extracellular vesicles are a hallmark of Sars-Cov-2 infection

G Cappellano, D Raineri, R Rolla, M Giordano… - Cells, 2021 - mdpi.com
Sars-Cov-2 infection causes fever and cough that may rapidly lead to acute respiratory
distress syndrome (ARDS). Few biomarkers have been identified but, unfortunately, these …

CD66b+/CD68+ circulating extracellular vesicles, lactate dehydrogenase and neutrophil‐to‐lymphocyte ratio can differentiate coronavirus disease 2019 severity …

R Suades, MF Greco, P Prieto, T Padró… - Journal of …, 2024 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) has been a major public health burden. We
hypothesised that circulating extracellular vesicles (cEVs), key players in health and …

Proteomics of serum-derived extracellular vesicles are associated with the severity and different clinical profiles of patients with COVID-19: An exploratory secondary …

AFP Leme, S Yokoo, AGC Normando, JVS Ormonde… - Cytotherapy, 2024 - Elsevier
Background aims Coronavirus disease 2019 (COVID-19) is characterized by a broad
spectrum of clinical manifestations with the potential to progress to multiple organ …

Proteomic profile of procoagulant extracellular vesicles reflects complement system activation and platelet hyperreactivity of patients with severe COVID-19

ECS Moraes, R Martins-Gonçalves, LR Silva… - Frontiers in Cellular …, 2022 - frontiersin.org
Background Extracellular vesicles (EVs) are a valuable source of biomarkers and display
the pathophysiological status of various diseases. In COVID-19, EVs have been explored in …

Longitudinal trend of plasma concentrations of extracellular vesicles in patients hospitalized for COVID-19

E Campello, CM Radu, C Simion, L Spiezia… - Frontiers in Cell and …, 2022 - frontiersin.org
Plasma concentrations of extracellular vesicles (EVs) originating from cells involved in
COVID-19-associated coagulopathy (CAC), their longitudinal trend and association with …

[HTML][HTML] The potential role of extracellular vesicles in COVID-19 associated endothelial injury and pro-inflammation

B Krishnamachary, C Cook, L Spikes, P Chalise… - medRxiv, 2020 - ncbi.nlm.nih.gov
COVID-19 infection caused by the novel severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has resulted in a global pandemic with the number of deaths growing …

Extracellular vesicles of COVID-19 patients reflect inflammation, thrombogenicity, and disease severity

A Aharon, A Dangot, F Kinaani, M Zavaro… - International Journal of …, 2023 - mdpi.com
Severe COVID-19 infections present with cytokine storms, hypercoagulation, and acute
respiratory distress syndrome, with extracellular vesicles (EVs) being involved in …

Binding of phosphatidylserine‐positive microparticles by PBMCs classifies disease severity in COVID‐19 patients

L Rausch, K Lutz, M Schifferer… - Journal of …, 2021 - Wiley Online Library
Infection with SARS‐CoV‐2 is associated with thromboinflammation, involving thrombotic
and inflammatory responses, in many COVID‐19 patients. In addition, immune dysfunction …