RNA m5C methylation: a potential modulator of innate immune pathways in hepatocellular carcinoma

S Meng, B Jiangtao, W Haisong, L Mei, Z Long… - Frontiers in …, 2024 - frontiersin.org
RNA 5-methylcytosine (m5C) methylation plays a crucial role in hepatocellular carcinoma
(HCC). As reported, aberrant m5C methylation is closely associated with the progression …

Vital roles of m5C RNA modification in cancer and immune cell biology

X Gu, X Ma, C Chen, J Guan, J Wang, S Wu… - Frontiers in …, 2023 - frontiersin.org
RNA modification plays an important role in epigenetics at the posttranscriptional level, and
5-methylcytosine (m5C) has attracted increasing attention in recent years due to the …

[HTML][HTML] Comprehensive Analysis of the Immune Infiltrates and PD-L1 of m6A RNA Methylation Regulators in Hepatocellular Carcinoma

Y Xu, X He, J Deng, L Xiong, Y Li, X Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Recently, N 6-methyladenosine (m6A) RNA methylation in eukaryotic mRNA has become
increasingly obvious in the pathogenesis and prognosis of cancer. Moreover, tumor …

[HTML][HTML] Dynamics of m6A RNA methylome on the hallmarks of hepatocellular carcinoma

E Sivasudhan, N Blake, ZL Lu, J Meng… - Frontiers in Cell and …, 2021 - frontiersin.org
Epidemiological data consistently rank hepatocellular carcinoma (HCC) as one of the
leading causes of cancer-related deaths worldwide, often posing severe economic burden …

RNA m6A methylation regulator-mediated modification patterns and tumor microenvironment characterization in hepatocellular carcinoma

Z Yan, Z Qin - 2023 - researchsquare.com
Background Mounting evidence has emphasized the relationship between RNA N 6-
methyladenosine (m 6 A) methylation modification and tumor immune regulation. However …

[HTML][HTML] N6-methyladenosine (m6A) modification in hepatocellular carcinoma

H Ma, Y Hong, Z Xu, Z Weng, Y Yang, D Jin… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is one of the deadliest cancers of human, the tumor-related
death of which ranks third among the common malignances. N 6 methyladenosine (m 6 A) …

[HTML][HTML] N6-methyladenosine (m6A)-mediated messenger RNA signatures and the tumor immune microenvironment can predict the prognosis of hepatocellular …

S Shen, J Yan, Y Zhang, Z Dong, J Xing… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background N6-methyladenosine (m6A)-mediated ribonucleic acid (RNA) methylation is
considered to be the most significant and abundant epigenetic modification in eukaryotic …

[HTML][HTML] RNA N6-methyladenosine patterns in hepatocellular carcinoma reveal a distinct immune infiltration landscape and clinical significance

H Zhao, Q Zhou, C Shi, Y Shao, J Ni… - … Medical Journal of …, 2021 - ncbi.nlm.nih.gov
Background RNA N6-methyladenosine (m 6 A) methylation, the most abundant and
prominent form of epigenetic modification, is involved in hepatocellular carcinoma (HCC) …

[HTML][HTML] METTL3 inhibits antitumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer

H Chen, Y Pan, Q Zhou, C Liang, CC Wong, Y Zhou… - Gastroenterology, 2022 - Elsevier
Background & Aims N 6-Methyladenosine (m 6 A) is the most prevalent RNA modification
and recognized as an important epitranscriptomic mechanism in colorectal cancer (CRC) …

m6A regulator-mediated methylation modification highlights immune infiltration patterns for predicting risk in hepatocellular carcinoma

D Zhou, Y Wang, W Wei, W Zhou, J Gu, Y Kong… - Journal of Cancer …, 2023 - Springer
Background Increasing studies have demonstrated the biological function of RNA N6-
methyladenosine (m6A) modifications in tumorigenesis. However, the potential role of m6A …