Background Elderly people are known to be vulnerable to virus infection. However, this has
not been appropriately tested in in vitro studies due to a lack of appropriate virus infection …

Although respiratory syncytial virus (RSV) is a major human respiratory pathogen, our
knowledge of how it causes disease in humans is limited. Airway epithelial cells are the …

Human respiratory syncytial virus (HRSV) is the leading cause of bronchiolitis in infants. Two
subgroups of HRSV (A and B) routinely cocirculate. Most research has been performed with …

In addition to the acute manifestations of respiratory syncytial virus (RSV), persistent
infection may be associated with long-term complications in the development of chronic …

Elderly persons are more susceptible to RSV-induced pneumonia than young people, but
the molecular mechanism underlying this susceptibility is not well understood. In this study …

Respiratory syncytial virus (RSV) is a substantial cause of severe lower respiratory tract
infections in infants, young children, older adults, and immunocompromised individuals …

Background Respiratory syncytial virus (RSV) is a primary cause of morbidity and mortality
worldwide, affecting infants, young children, and immune-compromised patients; however …

Objectives We report the use of reconstituted 3D human airway epithelium cells (HuAECs) of
bronchial origin in an air–liquid interface to study respiratory syncytial virus (RSV) infection …

Background. Previous studies in mice showed that respiratory syncytial virus (RSV) infection
was associated with RSV RNA persistence. This study was designed to characterize the …

Background. Recent studies have demonstrated that respiratory syncytial virus (RSV) is a
significant cause of morbidity and mortality in the elderly. The cellular mechanisms that …