Biotechnological, biomedical, and agronomical applications of plant protease inhibitors with high stability: A systematic review

J Cotabarren, D Lufrano, MG Parisi, WD Obregón - Plant Science, 2020 - Elsevier
Protease inhibitors (PIs) are regulatory proteins found in numerous animal tissues and
fluids, plants, and microorganisms that reduce and inhibit the exacerbated and uncontrolled …

[HTML][HTML] Plant protease inhibitors in therapeutics-focus on cancer therapy

S Srikanth, Z Chen - Frontiers in pharmacology, 2016 - frontiersin.org
Plants are known to have many secondary metabolites and phytochemical compounds
which are highly explored at biochemical and molecular genetics level and exploited …

Proteinaceous protease inhibitors: structural features and multiple functional faces

GA Joanitti, SM Freitas, LP Silva - Current Enzyme Inhibition, 2006 - ingentaconnect.com
Protease inhibitors (PIs) are present in a wide variety of living organisms including
microorganisms, plants, and animals. These molecules act as regulators of endogenous …

Peptide-based protease inhibitors from plants

R Hellinger, CW Gruber - Drug discovery today, 2019 - Elsevier
Highlights•The human proteasome is the second largest drug target class.•Few prototypic
proteases are standard tools for the discovery of novel inhibitors.•Peptide protease inhibitors …

Characterization, biomedical and agricultural applications of protease inhibitors: A review

TN Shamsi, R Parveen, S Fatima - International journal of biological …, 2016 - Elsevier
Abstract This review describes Protease Inhibitors (PIs) which target or inhibit proteases,
protein digesting enzymes. These proteases play a crucial task in many biological events …

[图书][B] Plant protease inhibitors: significance in nutrition, plant protection, cancer prevention and genetic engineering

Y Birk - 2003 - books.google.com
Plant protease inhibitors are diverse in number and in specificity towards various proteolytic
enzymes. This book focuses on the isolation, structure, characterization, physiochemical and …

Protease inhibitors from plants as therapeutic agents-a review

MS Cid-Gallegos, LJ Corzo-Ríos… - Plant Foods for Human …, 2022 - Springer
Plant-based diets are a great source of protease inhibitors (PIs). Two of the most well-known
families of PIs are Bowman-Birk inhibitors (BBI) and Kunitz-type inhibitors (KTI). The first …

[HTML][HTML] Microbial and fungal protease inhibitors—current and potential applications

J Sabotič, J Kos - Applied microbiology and biotechnology, 2012 - Springer
Proteolytic enzymes play essential metabolic and regulatory functions in many biological
processes and also offer a wide range of biotechnological applications. Because of their …

[HTML][HTML] Plant serine protease inhibitors: biotechnology application in agriculture and molecular farming

M Clemente, MG Corigliano, SA Pariani… - International journal of …, 2019 - mdpi.com
The serine protease inhibitors (SPIs) are widely distributed in living organisms like bacteria,
fungi, plants, and humans. The main function of SPIs as protease enzymes is to regulate the …

Complementation of intramolecular interactions for structural–functional stability of plant serine proteinase inhibitors

RS Joshi, M Mishra, CG Suresh, VS Gupta… - Biochimica et Biophysica …, 2013 - Elsevier
Abstract Background Plant protease inhibitors (PIs) constitute a diverse group of proteins
capable of inhibiting proteases. Among PIs, serine PIs (SPIs) display stability and …