Immunization is a cornerstone of public health policy and is demonstrably highly cost-
effective when used to protect child health. Although it could be argued that immunology has …

The history of vaccination clearly demonstrates that vaccines have been highly successful in
preventing infectious diseases, reducing significantly the incidence of childhood diseases …

Vaccines have been one of the major revolutions in the history of mankind and, during the
twentieth century, they eliminated most of the childhood diseases that used to cause millions …

Six of the top ten leading causes of death in low resource settings could potentially be
prevented by vaccination. Development of vaccines for individuals in these populations is …

Vaccination against infectious diseases has changed the future of the human species,
saving millions of lives every year, both children and adults, and providing major benefits to …

At the current time, the field of vaccinology remains empirical in many respects. Vaccine
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …

Vaccines are considered to be one of the greatest public health achievements of the last
century. Depending on the biology of the infection, the disease to be prevented, and the …

Vaccines are public health interventions aimed at preventing infections-related mortality,
morbidity, and disability. While vaccines have been successfully designed for those …

In this issue of Immunity, a collection of detailed reviews summarizes needs, opportunities,
and roadblocks to the development of new vaccines, all in the context of our current …

Although the field of immunology developed in part from the early vaccine studies of Edward
Jenner, Louis Pasteur and others, vaccine development had largely become the province of …