Although the success of vaccination to date has been unprecedented, our inadequate
understanding of the details of the human immune response to immunization has resulted in …

Background There has been a long and successful history of vaccine use. Although the
concept of marshalling the host's immune system to fight off infections via vaccination is …

In this issue of Immunity, a collection of detailed reviews summarizes needs, opportunities,
and roadblocks to the development of new vaccines, all in the context of our current …

Technological advances in antigen discovery, genomics and immunological monitoring offer
tremendous potential for revolutionizing vaccine development. On 5–6 February 2014, 35 …

Vaccines represent one of the greatest triumphs of modern medicine. Despite the common
origins of vaccinology and immunology more than 200 years ago, the two disciplines have …

The immune system is a network of specialized cell types and tissues that communicates via
cytokines and direct contact, to orchestrate specific types of defensive responses. Until …

The science of immunology began in the 19th century. Louis Pasteur and Robert Koch
established that microorganisms were the actual cause of infectious diseases, which greatly …

Immune signature atlas of vaccines: learning from the good responders | Nature Immunology
Skip to main content Thank you for visiting nature.com. You are using a browser version with …

The last decade has witnessed tremendous progress in immunology and vaccinology,
owing to several scientific and technological breakthroughs. Systems vaccinology is a field …

The last decade witnessed an explosion in information concerning the mechanisms
underlying the host's immune response to invading microorganisms, as well as during …