A Potential Intracanal Medicament, 2-Hydroxyisocaproic Acid (HICA): Cytotoxicity, Genotoxicity, and Its Effect on SCAP Differentiation

C Smoczer, YK Park, JB Herrington, MA Askar… - Dentistry Journal, 2023 - mdpi.com
Intracanal medicaments with maximal antimicrobial efficacy and minimal damage to resident
stem cells are essential for successful regenerative endodontic procedures. 2 …

Cytotoxicity and genotoxicity of a new intracanal medicament, 2-hydroxyisocaproic acid–an in vitro study

D Selis, Y Pande, C Smoczer, M Wheater… - Journal of …, 2019 - Elsevier
Introduction A successful outcome of root canal therapy relies on effective disinfection of the
root canal system, including the use of intracanal medicaments, which vary in their …

Direct effect of intracanal medicaments on survival of stem cells of the apical papilla

NB Ruparel, FB Teixeira, CCR Ferraz, A Diogenes - Journal of endodontics, 2012 - Elsevier
INTRODUCTION: Regenerative endodontic procedures are an alternative treatment for
immature teeth with necrotic pulps. Typically, intracanal medicaments such as triple …

[PDF][PDF] In-vitro Evaluation for Effects of Intracanal Medicaments on Viability, Proliferation, and Differentiation of Stem Cells From Apical Papilla–A Systematic Review

M Rahul, N Tewari, V Mathur… - European …, 2022 - jag.journalagent.com
This systematic review aimed to evaluate the cytotoxicity of intracanal medicaments used for
root canal disinfection and assess their effect on the proliferation and differentiation potential …

[PDF][PDF] Cytotoxicity and genotoxicity of calcium hydroxide and two antibiotic pastes on human stem cells of the apical papilla

D Jamshidi, M Ansari, N Gheibi - European Endodontic …, 2021 - jag.journalagent.com
Objective: This study aimed to assess the cytotoxicity and genotoxicity of triple antibiotic
paste, double antibiotic paste and calcium hydroxide medicaments on human stem cells of …

Effects of intracanal antimicrobials on viability and differentiation of stem cells from the apical papilla: An in vitro study

G Raddall, I Mello, BM Leung - Journal of Endodontics, 2022 - Elsevier
Background Recent studies have indicated that intracanal antimicrobials used to disinfect
the root canal in regenerative endodontic therapies (RETs) may be cytotoxic to stem cells …

Evaluation of effectiveness of intracanal medicaments on viability of stem cells of apical papilla

G Jain, A Goel, B Rajkumar, RS Bedi… - Journal of Pharmacy …, 2020 - journals.lww.com
Introduction: Regeneration, in the field of endodontics, is the process of restoring and
maintaining both architectural form and biological functions of damaged tooth. Presently …

Interaction of intracanal medicaments with apical papilla stem cells: quantitative cytotoxicity assessment by methyl thiazolyl tetrazolium, trypan blue and lactate …

E Saberi, N Farhad-Mollashahi, M Saberi - Minerva stomatologica, 2019 - europepmc.org
Background Chemical residues often have cytotoxic effects on the stem cells. This study
aimed to assess the cytotoxic effects of intracanal medicaments on stem cells of the apical …

Effect of dentin conditioning with intracanal medicaments on survival of stem cells of apical papilla

RI Althumairy, FB Teixeira, A Diogenes - Journal of endodontics, 2014 - Elsevier
Introduction Regenerative endodontics is a valuable treatment modality for immature teeth
with pulpal necrosis. A common feature in regenerative cases is the use of intracanal …

Viability and stimulation of human stem cells from the apical papilla (hscaps) induced by silicate-based materials for their potential use in regenerative endodontics: A …

JL Sanz, L Forner, A Almudéver, J Guerrero-Gironés… - Materials, 2020 - mdpi.com
Blood clot formation in the apical third of the root canal system has been shown to promote
further root development and reinforcement of dentinal walls by the deposition of …