[HTML][HTML] Neurofilament light chain on intensive care admission is an independent predictor of mortality in COVID-19: a prospective multicenter study

T Sievert, I Didriksson, M Spångfors, G Lilja… - Intensive Care Medicine …, 2023 - Springer
Abstract Background Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP),
and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be …

[HTML][HTML] Blood neurofilament light chain and total tau levels at admission predict death in COVID-19 patients

R De Lorenzo, NI Loré, A Finardi, A Mandelli… - Journal of …, 2021 - Springer
Background and aims Patients infected with SARS-CoV-2 range from asymptomatic, to mild,
moderate or severe disease evolution including fatal outcome. Thus, early predictors of …

[HTML][HTML] Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19

AH Aamodt, EA Høgestøl, TH Popperud, JC Holter… - Journal of …, 2021 - Springer
Objective To test the hypotheses that blood biomarkers for nervous system injury, serum
concentrations of neurofilament light chain protein (NfL) and glial fibrillary acidic protein …

[HTML][HTML] Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an …

A Abdelhak, L Barba, M Romoli, P Benkert… - Journal of …, 2023 - Springer
Background and aims To investigate the prognostic value of blood neurofilament light chain
protein (NfL) levels in the acute phase of coronavirus disease 2019 (COVID-19). Methods …

[HTML][HTML] Serum neurofilament light is elevated in COVID-19 positive adults in the ICU and is associated with co-morbid cardiovascular disease, neurological …

M Hay, L Ryan, M Huentelman, J Konhilas… - Cardiology and …, 2021 - ncbi.nlm.nih.gov
In critically ill COVID-19 patients, the risk of long-term neurological consequences is just
beginning to be appreciated. While recent studies have identified that there is an increase in …

Prognostic value of serum/plasma neurofilament light chain for COVID‐19‐associated mortality

RR Masvekar, P Kosa, K Jin, K Dobbs… - Annals of Clinical …, 2022 - Wiley Online Library
Objective Given the continued spread of coronavirus 2, the early predictors of coronavirus
disease 19 (COVID‐19) associated mortality might improve patients' outcomes. Increased …

[HTML][HTML] Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19

Y Erben, M Prudencio, CP Marquez, KR Jansen-West… - IScience, 2022 - cell.com
Blood neurofilament light chain (NFL) is proposed to serve as an estimate of disease
severity in hospitalized patients with coronavirus disease 2019 (COVID-19). We show that …

Serum neurofilament light chain levels in the intensive care unit: comparison between severely ill patients with and without coronavirus disease 2019

R Sutter, L Hert, GM De Marchis… - Annals of …, 2021 - Wiley Online Library
There is emerging evidence for multifarious neurological manifestations of coronavirus
disease 2019 (COVID‐19), but little is known regarding whether they reflect structural …

Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19

M Prudencio, Y Erben, CP Marquez… - Science translational …, 2021 - science.org
Brain imaging studies of patients with COVID-19 show evidence of macro-and
microhemorrhagic lesions, multifocal white matter hyperintensities, and lesions consistent …

[HTML][HTML] Serum neurofilament light chain in COVID-19 and the influence of renal function

P Körtvelyessy, E Diekämper, K Ruprecht… - European journal of …, 2023 - Springer
COVID-19 is associated with various neurological symptoms. Serum neurofilament light
chain (sNfL) is a robust marker for neuroaxonal injury. Recent studies have shown that …