[HTML][HTML] Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death

F Sauve, S Nampoothiri, SA Clarke, D Fernandois… - …, 2023 - thelancet.com
Background We have recently demonstrated a causal link between loss of gonadotropin-
releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive …

[HTML][HTML] Testosterone deficiency is a risk factor for severe COVID-19

L Lanser, FR Burkert, L Thommes, A Egger… - Frontiers in …, 2021 - frontiersin.org
Background Male sex is related to increased COVID-19 severity and fatality although
confirmed infections are similarly distributed between men and women. The aim of this …

[HTML][HTML] Case report: hypothalamic amenorrhea following COVID-19 infection and review of literatures

P Facondo, V Maltese, A Delbarba, I Pirola… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection, responsible for the coronavirus disease 2019 (COVID-19), can
impair any organ system including endocrine glands. However, hypothalamic–pituitary …

[HTML][HTML] COVID-19 and neurological impairment: hypothalamic circuits and beyond

BM Mussa, A Srivastava, AJM Verberne - Viruses, 2021 - mdpi.com
In December 2019, a novel coronavirus known as severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) emerged in Wuhan, the capital of Hubei, China. The virus …

Low growth hormone secretion associated with post-acute sequelae SARS-CoV-2 infection (PASC) neurologic symptoms: A case-control pilot study

TJ Wright, RB Pyles, M Sheffield-Moore… - Molecular and Cellular …, 2024 - Elsevier
Objective To determine if patients that develop lingering neurologic symptoms of fatigue and
“brain fog” after initial recovery from coronavirus disease 2019 (COVID-19) have persistent …

[HTML][HTML] Testicular atrophy and hypothalamic pathology in COVID-19: possibility of the incidence of male infertility and HPG axis abnormalities

K Selvaraj, S Ravichandran, S Krishnan… - Reproductive …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19), which resulted from the pandemic outbreak
of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a massive …

The hypothalamus as a hub for putative SARS-CoV-2 brain infection

S Nampoothiri, F Sauve, G Ternier, D Fernandois… - BioRxiv, 2020 - biorxiv.org
Most patients with COVID-19, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), display neurological symptoms, and respiratory failure in certain cases could …

[HTML][HTML] SARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability

F Crunfli, VC Carregari, FP Veras, PH Vendramini… - MedRxiv, 2021 - medrxiv.org
One increasingly documented tendency of COVID-19 patients is to exhibit neuropsychiatric
and neurological symptoms. Here we found that anxiety and cognitive impairment are …

Effect of SARS-CoV-2 infection upon male gonadal function: a single center-based study

L Ma, W Xie, D Li, L Shi, Y Mao, Y Xiong, Y Zhang… - MedRxiv, 2020 - medrxiv.org
Since SARS-CoV-2 infection was first identified in December 2019, it spread rapidly and a
global pandemic of COVID-19 has occurred. ACE2, the receptor for entry into the target cells …

[HTML][HTML] Potential neurochemical and neuroendocrine effects of social distancing amidst the COVID-19 pandemic

L Wang, G Nabi, D Li - Frontiers in Endocrinology, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in December
2019. It was then declared a public health emergency of international concern on 30 th …