Mining electronic health records: towards better research applications and clinical care

PB Jensen, LJ Jensen, S Brunak - Nature Reviews Genetics, 2012 - nature.com
Clinical data describing the phenotypes and treatment of patients represents an underused
data source that has much greater research potential than is currently realized. Mining of …

Chapter 13: Mining electronic health records in the genomics era

JC Denny - PLoS computational biology, 2012 - journals.plos.org
The combination of improved genomic analysis methods, decreasing genotyping costs, and
increasing computing resources has led to an explosion of clinical genomic knowledge in …

The secondary use of electronic health records for data mining: Data characteristics and challenges

T Sarwar, S Seifollahi, J Chan, X Zhang… - ACM Computing …, 2022 - dl.acm.org
The primary objective of implementing Electronic Health Records (EHRs) is to improve the
management of patients' health-related information. However, these records have also been …

Extracting research-quality phenotypes from electronic health records to support precision medicine

WQ Wei, JC Denny - Genome medicine, 2015 - Springer
The convergence of two rapidly developing technologies-high-throughput genotyping and
electronic health records (EHRs)-gives scientists an unprecedented opportunity to utilize …

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER

S Denaxas, A Gonzalez-Izquierdo… - Journal of the …, 2019 - academic.oup.com
Abstract Objective Electronic health records (EHRs) are a rich source of information on
human diseases, but the information is variably structured, fragmented, curated using …

The use of electronic health records for psychiatric phenotyping and genomics

JW Smoller - American Journal of Medical Genetics Part B …, 2018 - Wiley Online Library
The widespread adoption of electronic health record (EHRs) in healthcare systems has
created a vast and continuously growing resource of clinical data and provides new …

[HTML][HTML] Semi-supervised learning of the electronic health record for phenotype stratification

BK Beaulieu-Jones, CS Greene - Journal of biomedical informatics, 2016 - Elsevier
Patient interactions with health care providers result in entries to electronic health records
(EHRs). EHRs were built for clinical and billing purposes but contain many data points about …

Using electronic health records to generate phenotypes for research

SA Pendergrass, DC Crawford - Current protocols in human …, 2019 - Wiley Online Library
Electronic health records contain patient‐level data collected during and for clinical care.
Data within the electronic health record include diagnostic billing codes, procedure codes …

Next-generation phenotyping of electronic health records

G Hripcsak, DJ Albers - Journal of the American Medical …, 2013 - academic.oup.com
The national adoption of electronic health records (EHR) promises to make an
unprecedented amount of data available for clinical research, but the data are complex …

Clinical research informatics and electronic health record data

RL Richesson, MM Horvath… - Yearbook of medical …, 2014 - thieme-connect.com
Objectives: The goal of this survey is to discuss the impact of the growing availability of
electronic health record (EHR) data on the evolving field of Clinical Research Informatics …