An aging-related immune phenotype (ARIP) has been defined as a decrease in naïve T cells
(TN) relative to the accumulation of memory T cells (TM). Recent research implicates ARIP …

Background Cellular changes in adaptive immune system accompany the process of aging
and contribute to an aging-related immune phenotype (ARIP) characterized by decrease in …

Background Psychosocial stress is thought to play a key role in the acceleration of
immunological aging. This study investigated the relationship between lifetime and past …

Background A reduced number of naïve T cells along with an accumulation of differentiated
cell types in aging have been described but little is known about the polyfunctionality of the T …

Personality has been related to health and mortality risk, which has created interest in the
biological pathways that could explain this relationship. Although a dysregulation of the …

Introduction Age-related immunosenescence is characterized by changes in immune cell
subsets and is associated with mortality. However, since immunosenescence is associated …

To investigate the association of immunosenescence with aged-related morbidity in the
elderly, a clinical study was conducted to analyze and compare the alterations in peripheral …

Background: Elderly individuals have an eroded immune system but whether immune
senescence is implicated with the development of frailty is unknown. The underlying …

Background Global life expectancy is rising, with the 60+ age group projected to hit 2 billion
by 2050. Aging impacts the immune system. A notable marker of immune system aging is …

Background Progressive age-associated change in frequencies and functional capacities of
immune cells is known as immunosenescence. Despite data linking chronic environmental …