Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …

Background. Inflammation plays a major role in both aging and chronic disease.
Longitudinal studies in very old people can improve our understanding of these processes …

Background. Chronic inflammation has been proposed as a biological mechanism
underlying the decline in physical function that occurs with aging. The purpose of this …

Background. Associations of inflammation with age-related pathologies are documented;
however, it is not understood how changes in inflammation over time impact healthy aging …

PURPOSE: To investigate whether interleukin-6 and C-reactive protein levels predict all-
cause and cause-specific mortality in a population-based sample of nondisabled older …

OBJECTIVES: To investigate whether interleukin‐6 (IL‐6), C‐reactive protein (CRP) and
tumor necrosis factor‐alpha (TNF‐α) protein levels predict all‐cause mortality in older …

Background Interleukin-6 (IL-6) may have a protective role in acute liver disease but a
detrimental effect in chronic liver disease. It is unknown whether IL-6 is associated with risk …

Background: The importance of chronic inflammation as a determinant of aging phenotypes
may have been underestimated in previous studies that used a single measurement of …

Chronic inflammation is associated with the aging process and numerous age-related
pathologies. We evaluated the effects of age, caloric restriction (CR), and exercise on …

Background Aging is one factor believed to contribute to processes that underlie chronic low-
grade inflammation in older adults. Moreover, more recent studies have suggested that …