Methods to quantify biological aging are emerging as new measurement tools for
epidemiology and population science and have been proposed as surrogate measures for …

Biological aging measures have been proposed as proxies for extension of healthy life span
in trials of geroprotective therapies that aim to slow aging. Several methods to measure …

Background: Measures to quantify changes in the pace of biological aging in response to
intervention are needed to evaluate geroprotective interventions for humans. Previously, we …

Biological age (BA), derived from molecular and physiological measurements, has been
proposed to better predict mortality and disease than chronological age (CA). In the present …

Quantification of biological aging has been proposed for population surveillance of age-
related decline in system integrity and evaluation of geroprotective therapies. However …

Estimates of biological age based on DNA methylation patterns, often referred to as
“epigenetic age”,“DNAm age”, have been shown to be robust biomarkers of age in humans …

Biological age is not always concordant with chronological age and the departures are of
interest for understanding how diseases and environmental insults affect tissue function …

Biological aging is the gradual, progressive decline in system integrity that occurs with
advancing chronological age, causing morbidity and disability. Measurements of the pace of …

Epigenetic alterations are a hallmark of aging and age‐related diseases. Computational
models using DNA methylation data can create “epigenetic clocks” which are proposed to …

Motivation Ageing is a biological and psychosocial process related to diseases and
mortality. It correlates with changes in DNA methylation (DNAm) in all human tissues …