Cytotoxic Activity from Curcuma zedoaria Through Mitochondrial Activation on Ovarian Cancer Cells

Y Shin, Y Lee - Toxicological research, 2013 - Springer
Abstract α-Curcumene is one of the physiologically active components of Curcuma zedoaria,
which is believed to perform anti-tumor activities, the mechanisms of which are poorly …

Curcumol induces apoptosis via caspases-independent mitochondrial pathway in human lung adenocarcinoma ASTC-a-1 cells

W Zhang, Z Wang, T Chen - Medical oncology, 2011 - Springer
Abstract Curcumol isolated from Rhizoma Curcumae, a common traditional Chinese
medicine, has been reported to possess antitumor effects, but little is known about the …

[HTML][HTML] Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates

S Bhaumik, R Anjum, N Rangaraj, BVV Pardhasaradhi… - FEBS letters, 1999 - Elsevier
Curcumin, the active ingredient of the rhizome of Curcuma longa has anti-inflammatory,
antioxidant and antiproliferative activities. Although its precise mode of action remains …

Mechanisms of curcumin-induced apoptosis of Ehrlich's ascites carcinoma cells

S Pal, T Choudhuri, S Chattopadhyay… - Biochemical and …, 2001 - Elsevier
Curcumin, the active ingredient from the spice turmeric (Curcuma longa Linn), is a potent
antioxidant and anti-inflammatory agent. It has been recently demonstrated to possess …

Bisdemethoxycurcumin‐induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria …

ST Yang, AC Huang, NY Tang, HC Liu… - Environmental …, 2016 - Wiley Online Library
Curcuminoids are the major natural phenolic compounds found in the rhizome of many
Curcuma species. Curcuminoids consist of a mixture of curcumin, demethoxycurcumin …

Induction of apoptotic death by curcumin in human tongue squamous cell carcinoma SCC‐4 cells is mediated through endoplasmic reticulum stress and mitochondria …

SW Ip, SY Wu, CC Yu, CL Kuo, CS Yu… - Cell Biochemistry …, 2011 - Wiley Online Library
Curcumin from the rhizome of the Curcuma longa plant has been noted for its chemo‐
preventative and chemo‐therapy activities, and it inhibits the growth of many types of human …

Induction of apoptosis by curcumin in murine myelomonocytic leukemia WEHI‐3 cells is mediated via endoplasmic reticulum stress and mitochondria‐dependent …

AC Huang, CL Chang, CS Yu, PY Chen… - Environmental …, 2013 - Wiley Online Library
Curcumin, derived from the food flavoring spice turmeric (Curcuma longa), has been shown
to exhibit anticancer activities and induce apoptosis in many types of cancer cell lines. In our …

DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the …

SS Lin, HP Huang, JS Yang, JY Wu, TC Hsai, CC Lin… - Cancer letters, 2008 - Elsevier
Curcumin, a major component of the Curcuma species, is known to have antioxidant, anti-
inflammatory properties and induce apoptosis of cancer cells, however, the precise …

Curcumin inhibits proliferation and induces apoptosis of human colorectal cancer cells by activating the mitochondria apoptotic pathway

L Guo, X Chen, Y Hu, Z Yu, D Wang… - Phytotherapy …, 2013 - Wiley Online Library
Curcumin, a natural plant extract from Curcuma longa, is known for its anti‐carcinogenic and
chemopreventive effects on a variety of experimental cancer models. In this study, we …

Curcumin induces apoptosis in a murine mammary gland adenocarcinoma cell line through the mitochondrial pathway

A Ibrahim, A El-Meligy, G Lungu, H Fetaih… - European journal of …, 2011 - Elsevier
Curcumin, a phenol in turmeric (Curcuma longa), has been studied for the last decade as a
potential anticancer drug. It has been shown to reduce viability of the highly malignant …