Depression is a chronic and debilitating condition that often emerges during adolescence, a
period of significant brain maturation. Few studies, however, have examined how …

Prior research has demonstrated associations between adolescent depression and
alterations in the white matter microstructure of fiber tracts implicated in emotion regulation …

Major depressive disorder (MDD) during adolescence is a common and disabling
psychiatric condition; yet, little is known about its neurobiological underpinning. Evidence …

High levels of depression during adolescence may contribute to the risk for future
depression later in life. This study examined the relationship between the developmental …

Evidence from post-mortem, genetic, neuroimaging, and non-human animal research
suggests that Major Depressive Disorder (MDD) is associated with abnormalities in brain …

Objective Despite the significant prevalence of adolescent depression, little is known about
the neuroanatomical basis of this disorder. Functional dysregulation in frontolimbic circuitry …

Objective: White matter microstructure alterations have recently been associated with
depressive episodes during adolescence, but it is unknown whether they predate …

The neurobiology of adolescent depression remains poorly understood. Initial studies
suggested impaired white matter microstructure in adults and adolescents, but findings have …

OBJECTIVE: Major depressive disorder (MDD) occurs frequently in adolescents, but the
neurobiology of depression in youth is poorly understood. Structural neuroimaging studies …

The association between depressive disorders and measures reflecting myelin content is
underexplored, despite growing evidence of associations with white matter tract integrity. We …