Early-life adversities, whether prenatal or postnatal exposure, have been linked to adverse
mental health outcomes later in life increasing the risk of several psychiatric disorders …

The early-life environment has important consequences on behavioral development.
Specifically, the adversity experienced during sensitive developmental periods in childhood …

An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …

Accumulating evidence suggests that adversities at critical periods in early life, both pre-and
postnatal, can lead to neuroendocrine perturbations, including hypothalamic-pituitary …

Adverse experiences during sensitive postnatal developmental periods can disrupt the
calibration of fundamental systems and increase the risk of a wide range of adult disease …

Longitudinal studies in humans demonstrate the association between prenatal and
postnatal experiences of adversity and long-term changes in neurodevelopment. These …

Highlights•Prenatal and early postnatal stress exposure can impact brain
development.•Early adversity can have enduring effects, often leading to adult …

The concept of biological embedding has gained substantial traction as a framework for
understanding the roots of complex multifactorial phenomena in health and disease. A body …

Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …

Human epidemiological studies and studies of animal models provide many examples by
which early life experiences influence health in a long-term manner, a concept known as …