Lung disease accounts for every sixth death globally. Profiling the molecular state of all lung
cell types in health and disease is currently revolutionizing the identification of disease …

The human lung cellular portfolio, traditionally characterized by cellular morphology and
individual markers, is highly diverse, with over 40 cell types and a complex branching …

Organ-and body-scale cell atlases have the potential to transform our understanding of
human biology. To capture the variability present in the population, these atlases must …

Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions …

The human lung plays vital roles in respiration, host defense, and basic physiology. Recent
technological advancements such as single-cell RNA sequencing and genetic lineage …

Single-cell transcriptomics has allowed unprecedented resolution of cell types/states in the
human lung, but their spatial context is less well defined. To (re) define tissue architecture of …

Although single-cell RNA sequencing studies have begun to provide compendia of cell
expression profiles,,,,,,,–, it has been difficult to systematically identify and localize all …

The recent advent of methods for high-throughput single-cell molecular profiling has
catalyzed a growing sense in the scientific community that the time is ripe to complete the …

Comprehensively characterizing the cellular composition and organization of tissues has
been a long-term scientific challenge that has limited our ability to study fundamental and …

We present a multiomic cell atlas of human lung development that combines single-cell RNA
and ATAC sequencing, high-throughput spatial transcriptomics, and single-cell imaging …