Dietary lipids may influence the abundance of circulating inflammatory microbial factors.
Hence, inflammation in white adipose tissue (WAT) induced by dietary lipids may be partly …

Background & Aims Consumption of a low-fiber, high-fat, Western-style diet (WSD) induces
adiposity and adipose inflammation characterized by increases in the M1: M2 macrophage …

Background Obesity is associated with accumulation of macrophages in white adipose
tissue (WAT), which contribute to the development of insulin resistance. Germ-free (GF) mice …

Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

Background & Aims While it is widely accepted that obesity is associated with low-grade
systemic inflammation, the molecular origin of the inflammation remains unknown. Here, we …

The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …

Gut microbiota, an integral part of the human body, comprise bacteria, fungi, archaea, and
protozoa. There is consensus that the disruption of the gut microbiota (termed “gut …

The gut microbiota play important roles in lipid metabolism and absorption. However, the
contribution of the small bowel microbiota of mammals to these diet-microbe interactions …

The gut microbiota plays a key role in host metabolism. Toll-like receptor 5 (TLR5), a
flagellin receptor, is required for gut microbiota homeostasis. Accordingly, TLR5-deficient …

Gut microbiota have recently been suggested to play a part in low-grade systemic
inflammation, which is considered a key risk factor for cardiometabolic disorders. Diet is …