Aging is classically conceptualized as an ever-increasing trajectory of damage accumulation
and loss of function, leading to increases in morbidity and mortality. However, recent in vitro …

Heterochronic parabiosis (HPB) is known for its functional rejuvenation effects across
several mouse tissues. However, its impact on biological age and long-term health is …

Ageing is the single greatest cause of disease and death worldwide, and understanding the
associated processes could vastly improve quality of life. Although major categories of …

Geroscience offers a counterpoint to the challenged pursuit of curing diseases of aging, by
focusing on slowing the biological aging process for extended healthspan earlier in life …

Identifying reliable biomarkers of aging is a major goal in geroscience. While the first
generation of epigenetic biomarkers of aging were developed using chronological age as a …

Aging is unmistakable and undeniable in mammals. Interestingly, mice develop cataracts,
muscle atrophy, osteoporosis, obesity, diabetes and cognitive deficits after just 2–3 postnatal …

The social and medical costs of the biological aging process are high and will rise rapidly in
coming decades, creating an enormous challenge to societies worldwide. In recent …

Aging is associated with distinct phenotypical, physiological, and functional changes,
leading to disease and death. The progression of aging-related traits varies widely among …

Age is the greatest risk factor for nearly every major cause of mortality in developed nations.
Despite this, most biomedical research focuses on individual disease processes without …

The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …