Y Shao, W Le - Molecular neurodegeneration, 2019 - Springer
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease of the central nervous system (CNS), which affects mostly older adults. In recent years, the …
T Hatano, S Saiki, A Okuzumi, RP Mohney… - Journal of Neurology …, 2016 - jnnp.bmj.com
Objective The pathogenesis of Parkinson's disease (PD) involves complex interactions between environmental and genetic factors. Metabolomics can shed light on alterations in …
Progression of Parkinson's disease (PD) is highly variable, indicating that differences between slow and rapid progression forms could provide valuable information for improved …
D Stoessel, C Schulte… - Frontiers in aging …, 2018 - frontiersin.org
Parkinson's disease (PD) shows high heterogeneity with regard to the underlying molecular pathogenesis involving multiple pathways and mechanisms. Diagnosis is still challenging …
Parkinson's disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although …
H Zhao, C Wang, N Zhao, W Li, Z Yang, X Liu… - … of Chromatography B, 2018 - Elsevier
The plasma of Parkinson's disease (PD) patients may contain various altered metabolites associated with the risk or progression of the disease. Characterization of the abnormal …
C Gonzalez-Riano, J Saiz, C Barbas… - npj Parkinson's …, 2021 - nature.com
The lack of knowledge about the onset and progression of Parkinson's disease (PD) hampers its early diagnosis and treatment. Metabolomics might shed light on the PD imprint …
Biomarker research in Parkinson's disease (PD) has long been dominated by measuring dopamine metabolites or alpha-synuclein in cerebrospinal fluid. However, these markers do …
L Hu, MX Dong, YL Huang, CQ Lu, Q Qian… - Frontiers in Molecular …, 2020 - frontiersin.org
Parkinson's disease (PD) is a common neurodegenerative disease in the elderly with a pathogenesis that remains unclear. We aimed to explore its pathogenesis through plasma …