[HTML][HTML] Duration of humoral immunity from smallpox vaccination and its cross-reaction with Mpox virus

E Li, X Guo, D Hong, Q Gong, W Xie, T Li… - … and Targeted Therapy, 2023 - nature.com
The ongoing pandemic caused by mpox virus (MPXV) has become an international public
health emergency that poses a significant threat to global health. The vaccinia virus Tiantan …

[HTML][HTML] Evaluation of cross-immunity to the mpox virus due to historic smallpox vaccination

G Matusali, E Petruccioli, E Cimini, F Colavita, A Bettini… - Vaccines, 2023 - mdpi.com
When the Mpox virus (MPXV) began spreading globally in 2022, it became critical to
evaluate whether residual immunity from smallpox vaccination provided cross-protection. To …

Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals

M Hubert, F Guivel-Benhassine, T Bruel, F Porrot… - Cell Host & Microbe, 2023 - cell.com
Mpox virus (MPXV) caused a multi-country outbreak in non-endemic areas in 2022.
Following historic success of smallpox vaccination with vaccinia virus (VACV)-based …

Profiling the acute phase antibody response against mpox virus in patients infected during the 2022 outbreak

F Colavita, G Matusali, V Mazzotta… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Information on the immune response during the mpox virus (MPXV) infection is still
scarce or limited to past studies when cross‐reactive immunity from smallpox vaccination …

The assessment on cross immunity with smallpox virus and antiviral drug sensitivity of the isolated mpox virus strain WIBP-MPXV-001 in China

Y Zeng, X Liu, Y Li, J Lu, Q Wu, D Dan… - Emerging Microbes & …, 2023 - Taylor & Francis
Since May 2022, human mpox cases have increased unexpectedly in non-endemic
countries. The first imported case of human mpox in Hong Kong was reported in September …

Mpox neutralizing antibody response to LC16m8 vaccine in healthy adults

E Morino, S Mine, N Tomita, Y Uemura… - NEJM …, 2024 - evidence.nejm.org
Background Vaccination against mpox (formerly known as monkeypox), an infectious
disease caused by the monkeypox virus (MPXV), is needed to prevent outbreaks and …

[HTML][HTML] Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults

I Sanz-Muñoz, L Sánchez-dePrada… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus
antibodies in 162 persons≥ 50 years of age in Spain; 68.5% had detectable antibodies …

[HTML][HTML] Cross-reactive immune responses to monkeypox virus induced by MVA vaccination in mice

F Gao, C He, M Liu, P Yuan, S Tian, M Zheng, L Zhang… - Virology Journal, 2023 - Springer
Mpox (monkeypox) infection cases increased recently in non-Mpox outbreak areas,
potentially causing an international threat. The desire to defend against a potential outbreak …

Efficacy of smallpox vaccines against Mpox infections in humans

MM Christodoulidou, NA Mabbott - Immunotherapy Advances, 2023 - academic.oup.com
The Mpox virus (MPXV) is endemic in certain countries in Central and West Africa, where
several mammalian species, especially rodents, are natural reservoirs. However, the MPXV …

Analogous humoral antigen recognition between monkeypox-infected and smallpox-vaccinated individuals

AD Otter, S Jones, B Hicks, D Bailey, H Callaby… - MedRxiv, 2022 - medrxiv.org
In early 2022, a cluster of Monkeypox (now termed MPOX) virus (MPXV) cases were
identified within the UK with no prior travel history to MPXV-endemic regions, suggesting …