Whole blood transcriptome analysis is a valuable approachin medical research, primarily
due to the ease of sample collection and the richness of the information obtained. Since the …

Blood circulates throughout the body via the peripheral tissues, contributes to host
homeostasis and maintains normal physiological functions, in addition to responding to …

Background: Analysis of gene expression in peripheral blood samples is increasingly being
applied in biomarker studies of disease diagnosis and prognosis. Although knowledge of …

In our genome-wide survey of gene expression in human peripheral blood cells using both
an expressed sequence tag (EST) and a microarray hybridization approach, we identified …

Background Genomes of men and women differ in only a limited number of genes located
on the sex chromosomes, whereas the transcriptome is far more sex-specific. Identification …

Background Readily accessible samples such as peripheral blood or cell lines are
increasingly being used in large cohorts to characterise gene expression differences …

Background Numerous studies have demonstrated significant differences in the expression
level across continental human populations. Most of published results were performed on B …

Peripheral blood is an attractive source for the discovery of disease biomarkers. Gene
expression profiling of whole blood or its components has been widely conducted for …

Abstract Objective Glycated hemoglobin (HbA 1c) is a stable index of chronic glycemic
status and hyperglycemia associated with progressive development of insulin resistance …

A repeated measures microarray design with 22 healthy, non-smoking volunteers (aging
32±5 years) was set up to study transcriptome profiles in whole blood samples. The results …