Facing up to the global challenges of ageing

L Partridge, J Deelen, PE Slagboom - Nature, 2018 - nature.com
Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

[HTML][HTML] Medical research: treat ageing

L Fontana, BK Kennedy, VD Longo, D Seals, S Melov - Nature, 2014 - nature.com
Medical research: Treat ageing | Nature Skip to main content Thank you for visiting nature.com.
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The demographic and biomedical case for late-life interventions in aging

MJ Rae, RN Butler, J Campisi, ADNJ De Grey… - Science translational …, 2010 - science.org
The social and medical costs of the biological aging process are high and will rise rapidly in
coming decades, creating an enormous challenge to societies worldwide. In recent …

From discoveries in ageing research to therapeutics for healthy ageing

J Campisi, P Kapahi, GJ Lithgow, S Melov, JC Newman… - Nature, 2019 - nature.com
For several decades, understanding ageing and the processes that limit lifespan have
challenged biologists. Thirty years ago, the biology of ageing gained unprecedented …

Aging as a biological target for prevention and therapy

N Barzilai, AM Cuervo, S Austad - Jama, 2018 - jamanetwork.com
Chronic health problems related to the unprecedented aging of the human population in the
21st century threaten to disrupt economies and degrade the quality of later life throughout …

[HTML][HTML] Aging: a common driver of chronic diseases and a target for novel interventions

BK Kennedy, SL Berger, A Brunet, J Campisi… - Cell, 2014 - ncbi.nlm.nih.gov
Mammalian aging can be delayed with genetic, dietary and pharmacologic approaches.
Given that the elderly population is dramatically increasing and that aging is the greatest risk …

Benchmarks for ageing studies

L Partridge, D Gems - Nature, 2007 - nature.com
Benchmarks for ageing studies | Nature Skip to main content Thank you for visiting nature.com.
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The future of ageing

L Hayflick - Nature, 2000 - nature.com
Advances in our knowledge of age-associated diseases have far outpaced advances in our
understanding of the fundamental ageing processes that underlie the vulnerability to these …

Quantification of biological aging in young adults

DW Belsky, A Caspi, R Houts… - Proceedings of the …, 2015 - National Acad Sciences
Antiaging therapies show promise in model organism research. Translation to humans is
needed to address the challenges of an aging global population. Interventions to slow …

[HTML][HTML] The business of anti-aging science

JP De Magalhães, M Stevens, D Thornton - Trends in biotechnology, 2017 - cell.com
Age-related conditions are the leading causes of death and health-care costs. Reducing the
rate of aging would have enormous medical and financial benefits. Myriad genes and …