Calcium (Ca2+) is a universal regulator of various cellular functions. In cardiomyocytes,
Ca2+ is the central element of excitation–contraction coupling, but also impacts diverse …

Calcium (Ca2+) is a critical regulator of cardiac myocyte function. Principally, Ca2+ is the
link between the electrical signals that pervade the heart and contraction of the myocytes to …

Calcium (Ca) is a universal intracellular second messenger. In muscle, Ca is best known for
its role in contractile activation. However, in recent years the critical role of Ca in other …

Rhythmic increases in intracellular Ca2+ concentration underlie the contractile function of
the heart. These heart muscle-wide changes in intracellular Ca2+ are induced and …

Cardiac calcium signalling Page 1 930 Biochemical Society Transactions (2003) Volume 31,
part 5 Cardiac calcium signalling MJ Berridge1 Laboratory of Molecular Signalling, The …

Calcium (Ca) is a multifunctional regulator of diverse cellular functions. In cardiac muscle Ca
is a direct central mediator of electrical activation, ion channel gating, and excitation …

No other inorganic molecule known in biology is considered as versatile as Ca2+. In a vast
majority of cell types, Ca2+ acts as a universal second messenger underlying critical cellular …

Ca2+ signaling pathways are well studied in cardiac myocytes, but not in cardiac fibroblasts.
The aim of the present study is to characterize Ca2+ signaling pathways in cultured human …

Myocardial calcium signalling is a vital component of the normal physiological function of the
heart. Key amongst the many roles calcium plays is its use as the primary signalling …

Adult cardiomyocytes exhibit complex Ca2+ homeostasis, enabling tight control of
contraction and relaxation. This intricate regulatory system develops gradually, with …