A synopsis on aging—Theories, mechanisms and future prospects

JP da Costa, R Vitorino, GM Silva, C Vogel… - Ageing research …, 2016 - Elsevier
Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

AA Cohen, BK Kennedy, U Anglas… - Mechanisms of ageing …, 2020 - Elsevier
At a recent symposium on aging biology, a debate was held as to whether or not we know
what biological aging is. Most of the participants were struck not only by the lack of …

The stress of aging

M Cesari, B Vellas, G Gambassi - Experimental gerontology, 2013 - Elsevier
Although the evolutionary theories of aging are quite well established, our knowledge about
how we age is still very limited. The abundance and heterogeneity of available mechanistic …

What is an anti-aging treatment?

D Gems - Experimental Gerontology, 2014 - Elsevier
Key objectives of biogerontology are to understand the biology of aging and to translate
scientific insight into interventions that improve late-life health—or anti-aging treatments. In …

[HTML][HTML] What if there's no such thing as “aging”?

AA Cohen, V Legault, T Fülöp - Mechanisms of ageing and development, 2020 - Elsevier
Are diseases caused by aging? What are the mechanisms of aging? Do all species age?
These hotly debated questions revolve around a unitary definition of aging. Because we use …

[图书][B] Understanding ageing

R Holliday - 1995 - books.google.com
This book presents a completely novel approach to the understanding of ageing, which
many believe is an unsolved problem in biology. It explains why ageing exists in animals …

[图书][B] Biology of aging: observations and principles

R Arking - 2006 - books.google.com
Robert Arking's Biology of Aging, 3rd edition, is an introductory text to the biology of aging
which gives advanced undergraduate and graduate students a thorough review of the entire …

The aging process and potential interventions to extend life expectancy

M Tosato, V Zamboni, A Ferrini… - Clinical interventions in …, 2007 - Taylor & Francis
Aging is commonly defined as the accumulation of diverse deleterious changes occurring in
cells and tissues with advancing age that are responsible for the increased risk of disease …

The meaning of adaptation in aging: insights from cellular senescence, epigenetic clocks and stem cell alterations

M Ogrodnik, VN Gladyshev - Nature Aging, 2023 - nature.com
With recent rapid progress in research on aging, there is increasing evidence that many
features commonly considered to be mechanisms or drivers of aging in fact represent …

Key signaling pathways in aging and potential interventions for healthy aging

M Yu, H Zhang, B Wang, Y Zhang, X Zheng, B Shao… - Cells, 2021 - mdpi.com
Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …