Sex‐specific aging in animals: perspective and future directions

AM Bronikowski, RP Meisel, PR Biga, JR Walters… - Aging …, 2022 - Wiley Online Library
Sex differences in aging occur in many animal species, and they include sex differences in
lifespan, in the onset and progression of age‐associated decline, and in physiological and …

Sex differences in longevity and aging

SN Austad - Handbook of the Biology of Aging, 2011 - Elsevier
Publisher Summary This chapter reviews the copious evidence for the robustness of
women's survival advantage, discusses some of the extant evolutionary and mechanistic …

[PDF][PDF] Sex differences in lifespan

SN Austad, KE Fischer - Cell metabolism, 2016 - cell.com
Sex differences in longevity can provide insights into novel mechanisms of aging, yet they
have been little studied. Surprisingly, sex-specific longevity patterns are best known in wild …

[HTML][HTML] Sex differences in biological aging with a focus on human studies

S Hägg, J Jylhävä - Elife, 2021 - elifesciences.org
Aging is a complex biological process characterized by hallmark features accumulating over
the life course, shaping the individual's aging trajectory and subsequent disease risks. There …

[HTML][HTML] Of mice and men: when it comes to studying ageing and the means to slow it down, mice are not just small humans

L Demetrius - EMBO reports, 2005 - embopress.org
All mammalian cells use similar molecular mechanisms to regulate growth, replication,
differentiation and death. Even specialized cells, such as fibroblasts or secretory epithelial …

Widespread sex dimorphism in aging and age-related diseases

NK Sampathkumar, JI Bravo, Y Chen, PS Danthi… - Human genetics, 2020 - Springer
Although aging is a conserved phenomenon across evolutionary distant species, aspects of
the aging process have been found to differ between males and females of the same …

Sex differences in adult lifespan and aging rates of mortality across wild mammals

JF Lemaître, V Ronget, M Tidière… - Proceedings of the …, 2020 - National Acad Sciences
In human populations, women consistently outlive men, which suggests profound biological
foundations for sex differences in survival. Quantifying whether such sex differences are also …

'Accelerated aging': a primrose path to insight?

RA Miller - Aging cell, 2004 - Wiley Online Library
Organism envy afflicts most researchers who work on aging in mice; how frustrating it is to
see the worm and fly biologists nail down milestone after milestone, citation after citation …

Does sexual selection shape sex differences in longevity and senescence patterns across vertebrates? A review and new insights from captive ruminants

M Tidière, JM Gaillard, DWH Müller, LB Lackey… - …, 2015 - academic.oup.com
In most mammals, both sexes display different survival patterns, often involving faster
senescence in males. Being under intense sexual competition to secure mating …

Gender and longevity: why do men die earlier than women? Comparative and experimental evidence

JC Regan, L Partridge - Best practice & research Clinical endocrinology & …, 2013 - Elsevier
Sex differences in lifespan exist world-wide, with women outliving men by more than a
decade in some countries. The gender gap is not a uniquely human phenomenon; most …