SN Austad - Handbook of the Biology of Aging, 2011 - Elsevier
Publisher Summary This chapter reviews the copious evidence for the robustness of women's survival advantage, discusses some of the extant evolutionary and mechanistic …
SN Austad, KE Fischer - Cell metabolism, 2016 - cell.com
Sex differences in longevity can provide insights into novel mechanisms of aging, yet they have been little studied. Surprisingly, sex-specific longevity patterns are best known in wild …
S Hägg, J Jylhävä - Elife, 2021 - elifesciences.org
Aging is a complex biological process characterized by hallmark features accumulating over the life course, shaping the individual's aging trajectory and subsequent disease risks. There …
All mammalian cells use similar molecular mechanisms to regulate growth, replication, differentiation and death. Even specialized cells, such as fibroblasts or secretory epithelial …
NK Sampathkumar, JI Bravo, Y Chen, PS Danthi… - Human genetics, 2020 - Springer
Although aging is a conserved phenomenon across evolutionary distant species, aspects of the aging process have been found to differ between males and females of the same …
In human populations, women consistently outlive men, which suggests profound biological foundations for sex differences in survival. Quantifying whether such sex differences are also …
RA Miller - Aging cell, 2004 - Wiley Online Library
Organism envy afflicts most researchers who work on aging in mice; how frustrating it is to see the worm and fly biologists nail down milestone after milestone, citation after citation …
In most mammals, both sexes display different survival patterns, often involving faster senescence in males. Being under intense sexual competition to secure mating …
JC Regan, L Partridge - Best practice & research Clinical endocrinology & …, 2013 - Elsevier
Sex differences in lifespan exist world-wide, with women outliving men by more than a decade in some countries. The gender gap is not a uniquely human phenomenon; most …