[HTML][HTML] Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: Evidence from mixture approaches

W Shi, X Gao, Y Cao, Y Chen, Q Cui, F Deng… - Environment …, 2022 - Elsevier
Background Air pollution is associated with accelerated biological ages determined by DNA
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …

Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study

JC Nwanaji-Enwerem, E Colicino… - Environmental …, 2016 - academic.oup.com
Background: Ambient particles have been shown to exacerbate measures of biological
aging; yet, no studies have examined their relationships with DNA methylation age (DNAm …

[HTML][HTML] Epigenetic aging biomarkers and occupational exposure to benzene, trichloroethylene and formaldehyde

L Van der Laan, A Cardenas, R Vermeulen… - Environment …, 2022 - Elsevier
Epigenetic aging biomarkers are associated with increased morbidity and mortality. We
evaluated if occupational exposure to three established chemical carcinogens is associated …

[HTML][HTML] The early-life exposome and epigenetic age acceleration in children

P de Prado-Bert, C Ruiz-Arenas, M Vives-Usano… - Environment …, 2021 - Elsevier
The early-life exposome influences future health and accelerated biological aging has been
proposed as one of the underlying biological mechanisms. We investigated the association …

[HTML][HTML] Short-and intermediate-term exposure to ambient fine particulate elements and leukocyte epigenome-wide DNA methylation in older men: the Normative …

C Wang, A Cardenas, JN Hutchinson, A Just… - Environment …, 2022 - Elsevier
Background Several epigenome-wide association studies (EWAS) of ambient particulate
matter with aerodynamic diameter≤ 2.5 µm (PM 2.5) have been reported. However, EWAS …

[HTML][HTML] Air pollution, particulate matter composition and methylation-based biologic age

AJ White, JK Kresovich, JP Keller, Z Xu… - Environment …, 2019 - Elsevier
Background Epigenetic age, as defined by DNA methylation, may be influenced by air
pollution exposure. Objective To evaluate the relationship between NO 2, particulate matter …

Exposure to polycyclic aromatic hydrocarbons and accelerated DNA methylation aging

J Li, X Zhu, K Yu, H Jiang, Y Zhang… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Aging is related to an increased risk of morbidity and mortality and is affected
by environmental factors. Exposure to polycyclic aromatic hydrocarbons (PAHs) is …

Associations of annual ambient PM2. 5 components with DNAm PhenoAge acceleration in elderly men: The Normative Aging Study

C Wang, P Koutrakis, X Gao, A Baccarelli… - Environmental …, 2020 - Elsevier
Current studies indicate that long-term exposure to ambient fine particulate matter (PM 2.5)
is related with global mortality, yet no studies have explored relationships of PM 2.5 and its …

The associations of multiple metals mixture with accelerated DNA methylation aging

L Xiao, G Zan, X Feng, Y Bao, S Huang, X Luo… - Environmental …, 2021 - Elsevier
Aging is a leading cause of mortality for the elderly and DNA methylation age is reported to
be predictive of biological aging. However, few studies have investigated the associations …

Short-Term Exposure of PM2.5 and Epigenetic Aging: A Quasi-Experimental Study

X Gao, J Huang, A Cardenas, Y Zhao… - Environmental …, 2022 - ACS Publications
Epigenetic age (EA) is an emerging DNA methylation-based biomarker of biological aging,
but whether EA is causally associated with short-term PM2. 5 exposure remains unknown …