Aging, for virtually all life, is inescapable. However, within populations, biological aging rates
vary. Understanding sources of variation in this process is central to understanding the …

In mammals, females generally live longer than males. Nevertheless, the mechanisms
underpinning sex-dependent longevity are currently unclear. Epigenetic clocks are powerful …

Age‐associated DNA‐methylation profiles have been used successfully to develop highly
accurate biomarkers of age (" epigenetic clocks") in humans, mice, dogs, and other species …

Biological ageing and its mechanistic underpinnings are of immense biomedical and
ecological significance. Ageing involves the decline of diverse biological functions and …

All humans age, but how we age—and how fast—differs considerably from person to
person. This deviation between apparent age and chronological age is often referred to as …

A central prediction of evolutionary theory is that energy invested into reproduction comes at
the expense of somatic maintenance and repair, accelerating biological aging. Supporting …

Epigenetic changes during ageing have been characterized by multiple epigenetic clocks
that allow the prediction of chronological age based on methylation status. Despite their …

Epigenetic clocks are mathematically derived age estimators that are based on
combinations of methylation values that change with age at specific CpGs in the genome …

In wild animal conservation, knowing the age of an individual animal is extremely beneficial.
However, estimating the age is difficult for many species. Recently, epigenetics-based …

Background DNA methylation changes at a discrete set of sites in the human genome are
predictive of chronological and biological age. However, it is not known whether these …