Background Retrospective analyses suggest that pulmonary embolism is ruled out by a d-
dimer level of less than 1000 ng per milliliter in patients with a low clinical pretest probability …

Background We designed a diagnostic strategy, based on clinical probability and D-dimer
concentration, to select patients who were unlikely to have pulmonary embolism (PE), before …

Background The d-dimer test is widely applied in the diagnostic workup of patients with
suspected pulmonary embolism (PE). The objective of this study was to investigate how …

The plasma level of D-dimer, a fibrin degradation product (FDP), is nearly always increased
in the presence of acute pulmonary embolism (PE). Hence, a normal D-dimer level (below a …

Background Validated diagnostic algorithms in patients with suspected pulmonary embolism
are often not used correctly or only benefit subgroups of patients, leading to overuse of …

In the past 10 or 15 years, the proportion of cases diagnosed with pulmonary embolism (PE)
among suspected/tested patients has steadily decreased, an evolution that paralleled the …

Importance D-dimer measurement is an important step in the diagnostic strategy of clinically
suspected acute pulmonary embolism (PE), but its clinical usefulness is limited in elderly …

Background: It may be safe to omit additional diagnostic testing in selected patients with
suspected pulmonary embolism (PE) who have a negative d-dimer test, but this approach …

Study objective To determine whether measurement of D-dimer, using an enzyme-linked
immunosorbent assay (ELISA) with a cutoff of 300 ng/ml, and a latex agglutination assay …

Background: Increasing the threshold to define a positive D‐dimer could reduce
unnecessary computed tomographic pulmonary angiography (CTPA) for a suspected …