The critical role of the coronary microvascular compartment and its invasive functional
assessment has become apparent in light of the significant proportion of patients presenting …

The coronary microvasculature plays a key role in determining and modulating coronary
blood flow across the spectrum of myocardial demand. Our understanding of this complex …

A growing amount of data is increasingly showing the relevance of coronary microvascular
dysfunction (CMVD) in several clinical contexts. This article reviews techniques and clinical …

Coronary microvascular dysfunction (CMD) is related to a broad variety of clinical scenarios
in which cardiac microvasculature is morphologically and functionally affected, and it is …

Obstructive disease of the epicardial coronary arteries was recognized as the cause of
angina pectoris> 2 centuries ago, and sudden thrombotic occlusion of an epicardial …

Angina has traditionally been thought to be caused by obstructive coronary artery disease
(CAD). However, a substantial number of patients with angina are found to not have …

Many patients undergoing coronary angiography because of chest pain syndromes,
believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries …

In the past two decades a number of studies have shown that abnormalities in the function
and structure of coronary microcirculation can be detected in several cardiovascular …

Diffuse and focal epicardial coronary disease and coronary microvascular abnormalities
may exist side-by-side. Identifying the contributions of each of these three players in the …

Coronary microvascular dysfunction (CMD) is a prevalent cause of ischemic heart disease
and is associated with poorer quality of life and worse patient outcomes. Both functional and …