Telomeres (TLs) reside at the end of chromosomes and are complexes of deoxyribonucleic
acid (DNA). TLs oversee cell replication and the lifespan of a cell, are involved in multiple …

Telomeres are DNA-protein structures that form protective caps at the end of eukaryotic
chromosomes. They constitute the safeguards of chromosome degradation and are …

Telomeres in telomerase-negative cells shorten during DNA replication in vitro due to
numerous causes including the inability of DNA polymerases to fully copy the lagging …

Aim The telomere is a structure present at the ends of chromosomes, and is known to
shorten with aging and successive rounds of cell division. However, very little is known …

Telomeres in most human cell types shorten during DNA replication in vitro because of
various factors including the inability of DNA polymerases to fully copy the lagging strand …

Telomeres, at the ends of chromosomes and strands of genetic material, become shorter as
cells divide in the process of aging. Telomere length has been considered as a biological …

Background: Several observational studies have found leukocyte telomere length (TL) to be
associated with Alzheimer's diseases (AD) or dementia. However, these findings were …

Telomeres, ribonucleoprotein complexes that cap eukaryotic chromosomes, typically
shorten in leukocytes with aging. Aging is a primary risk factor for neurodegenerative …

Association of telomere shortening with overall dementia or Alzheimer's disease is
described controversially and the pathophysiologic relevance is unclear. Whether patients …

Background. A great deal of attention has been focused on telomeres in relation to cellular
aging, immortality, and cancer. However, there is no simple link between telomeres and …