Re-wilding Model Organisms: Opportunities to test causal mechanisms in social determinants of health and aging

MN Zipple, CC Vogt, MJ Sheehan - Neuroscience & Biobehavioral …, 2023 - Elsevier
Social experiences are strongly associated with individuals' health, aging, and survival in
many mammalian taxa, including humans. Despite their role as models of many other …

The biology of aging in a social world: Insights from free-ranging rhesus macaques

LE Newman, C Testard, AR DeCasien, KL Chiou… - Neuroscience & …, 2023 - Elsevier
Social adversity can increase the age-associated risk of disease and death, yet the
biological mechanisms that link social adversities to aging remain poorly understood. Long …

The fortunes and misfortunes of social life across the life course: a new era of research from field, laboratory and comparative studies

A Bartolomucci, J Tung, KM Harris - Neuroscience & Biobehavioral …, 2024 - Elsevier
Social gradients in health and aging have been reported in studies across many human
populations, and-as the papers included in this special collection highlight–also occur …

Early life adversities and lifelong health outcomes: A review of the literature on large, social, long-lived nonhuman mammals

AM Dettmer, DE Chusyd - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Social nonhuman animals are powerful models for studying underlying factors related to
lifelong health outcomes following early life adversities (ELAs). ELAs can be linked to …

Social determinants of health and survival in humans and other animals

N Snyder-Mackler, JR Burger, L Gaydosh, DW Belsky… - Science, 2020 - science.org
BACKGROUND The social environment shapes human health, producing strong
relationships between social factors, disease risk, and survival. The strength of these links …

Advancing methods for the biodemography of aging within social contexts

R Hernández-Pacheco, UK Steiner, AG Rosati… - Neuroscience & …, 2023 - Elsevier
Several social dimensions including social integration, status, early-life adversity, and their
interactions across the life course can predict health, reproduction, and mortality in humans …

Animal models in aging research: a critical examination

R Buffenstein, YH Edrey, PL Larsen - Sourcebook of models for …, 2008 - Springer
Understanding why different organisms show diverse rates of aging may provide useful
insights into basic aging processes. Biogerontologists have converged on a few model …

Rhesus macaques as a tractable physiological model of human ageing

KL Chiou, MJ Montague… - … of the Royal …, 2020 - royalsocietypublishing.org
Research in the basic biology of ageing is increasingly identifying mechanisms and
modifiers of ageing in short-lived organisms such as worms and mice. The ultimate goal of …

Mouse models in aging research

K Flurkey, JM Currer, DE Harrison - The mouse in biomedical research, 2007 - Elsevier
Publisher Summary In invertebrates, the molecular genetic pathways that regulate life span
and senescence are being identified; surprisingly, they are conserved through evolution. In …

Opportunities for new insight into aging from the naked mole-rat and other non-traditional models

R Buffenstein, JG Ruby - Nature aging, 2021 - nature.com
Opportunities for new insight into aging from the naked mole-rat and other non-traditional models
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