Revealing the interaction mechanisms between anticancer drugs and target DNA molecules
at the single-molecule level is a hot research topic in the interdisciplinary fields of …

Docetaxel (DOC) is one of the second-generation antineoplastic drugs of the taxanes family
with excellent antitumor activity. However, the mechanism of DOC inducing tumor cell …

It is of great fundamental significance and practical application to understand the binding
sites and dynamic process of the interaction between doxorubicin (DOX) and DNA …

Bendamustine (BENDA) is a bifunctional alkylating agent with alkylating and purinergic
antitumor activity, which exerts its anticancer effects by direct binding to DNA, but the …

The forkhead box (FOX) transcription factor is a family of tumor suppressors that negatively
regulates the tumorigenesis activity of prostate cancer; stabilization of FOX–DNA complex …

It is noteworthy to understand the details of interactions between antitumor drugs and DNA
because the binding modes and affinities affect their antitumor activities. Here, The …

Exploration of the interaction of a thalidomide analogue immunomodulatory and anti-
angiogenic drug pomalidomide (POD) with calf thymus DNA (CT-DNA) was carried out …

Binding of voglibose (VOG), an alpha glucosidase inhibitor, with CT-DNA has been
investigated using various spectroscopic techniques including UV–Vis, fluorescence and …

Deoxyribonucleic acid (DNA) is consisted of two long polymer strands of sugar 2-
deoxyribose, phosphate, purine, and pyrimidine bases. As a significant biomacromolecule in …

In this work, we report the interaction of a fluorescent ZnO–Au nanocomposite with
deoxyribonucleic acid (DNA), leading to AT-specific DNA interaction, which is hitherto not …