Identification and experimental validation of ferroptosis-related gene SLC2A3 is involved in rheumatoid arthritis

J Xiang, H Chen, Z Lin, J Chen, L Luo - European Journal of Pharmacology, 2023 - Elsevier
Background Ferroptosis, an iron-dependent manner of lipid peroxidative cell death, has
recently been reported to be strongly associated with rheumatoid arthritis (RA). Targeted …

[HTML][HTML] Identification of potential ferroptosis-associated biomarkers in rheumatoid arthritis

X He, J Zhang, M Gong, Y Gu, B Dong, X Pang… - Frontiers in …, 2023 - frontiersin.org
Background Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by
inflammation and gradual joint degeneration, resulting in function disability. Recently …

[HTML][HTML] Identification of ferroptosis related markers by integrated bioinformatics analysis and In vitro model experiments in rheumatoid arthritis

J Xia, L Zhang, T Gu, Q Liu, Q Wang - BMC Medical Genomics, 2023 - Springer
Background Rheumatoid arthritis (RA) is an autoimmune disease characterized by
destructive and symmetrical joint diseases and synovitis. This research attempted to explore …

[HTML][HTML] Ferroptosis-related molecular clusters and diagnostic model in rheumatoid arthritis

M Xie, C Zhu, Y Ye - International Journal of Molecular Sciences, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by synovitis, joint
damage and deformity. A newly described type of cell death, ferroptosis, has an important …

[HTML][HTML] Identification and verification of ferroptosis-related genes in the synovial tissue of osteoarthritis using bioinformatics analysis

L Xia, N Gong - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Background: Osteoarthritis (OA) is a major factor causing pain and disability. Studies
performed to date have suggested that synovitis is possibly a critical OA-related pathological …

[HTML][HTML] Identification of SLC3A2 as a potential therapeutic target of osteoarthritis involved in ferroptosis by integrating bioinformatics, clinical factors and experiments

H Liu, Z Deng, B Yu, H Liu, Z Yang, A Zeng, M Fu - Cells, 2022 - mdpi.com
Osteoarthritis (OA) is a type of arthritis that causes joint pain and limited mobility. In recent
years, some studies have shown that the pathological process of OA chondrocytes is related …

[HTML][HTML] Analysis of ferroptosis-associated genes in Crohn's disease based on bioinformatics

X Ji, S Ma, X Sun, D Yu, Y Song, R Li - Frontiers in Medicine, 2023 - frontiersin.org
Background: Ferroptosis, a novel mode of apoptosis has recently been shown to be
associated with fibrosis, tumor, cardiovascular and other diseases. In this study, using …

[HTML][HTML] Characterization and role exploration of ferroptosis-related genes in osteoarthritis

X Wang, T Liu, C Qiu, S Yu, Y Zhang… - Frontiers in Molecular …, 2023 - frontiersin.org
Osteoarthritis (OA), viewing as a degenerative aseptic inflammatory disease, is
characterized by joint pain and inflammation that significantly affects the quality of patients' …

[HTML][HTML] Machine learning identifies ferroptosis-related genes as potential diagnostic biomarkers for osteoarthritis

Y Qiu, J Yao, L Li, J Meng, Y Cai, J Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Osteoarthritis (OA) is one of the most common forms of degenerative arthritis
and a major cause of pain and disability. Ferroptosis, a novel mode of cell death, has been …

[HTML][HTML] Specificity protein 1-mediated ACSL4 transcription promoted the osteoarthritis progression through suppressing the ferroptosis of chondrocytes

W He, X Lin, K Chen - Journal of Orthopaedic Surgery and Research, 2023 - Springer
Background Chondrocytes are the main cell damage type involved in the occurrence and
development of osteoarthritis (OA). Ferroptosis has been confirmed to be related to many …