Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy

ML Elliott, A Caspi, RM Houts, A Ambler, JM Broadbent… - Nature aging, 2021 - nature.com
Some humans age faster than others. Variation in biological aging can be measured in
midlife, but the implications of this variation are poorly understood. We tested associations …

Is 60 the new 50? Examining changes in biological age over the past two decades

ME Levine, EM Crimmins - Demography, 2018 - read.dukeupress.edu
Increasing life expectancy has been interpreted as improving health of a population.
However, mortality is not always a reliable proxy for the pace of aging and could instead …

Frailty, fitness and late-life mortality in relation to chronological and biological age

AB Mitnitski, JE Graham, AJ Mogilner, K Rockwood - BMC geriatrics, 2002 - Springer
Background People age at remarkably different rates, but how to estimate trajectories of
senescence is controversial. Methods In a secondary analysis of a representative cohort of …

The longitudinal study of aging in human young adults: knowledge gaps and research agenda

TE Moffitt, DW Belsky, A Danese… - … of Gerontology Series …, 2017 - academic.oup.com
Background: To prevent onset of age-related diseases and physical and cognitive decline,
interventions to slow human aging and extend health span must eventually be applied to …

Inconvenient truths about human longevity

SJ Olshansky, BA Carnes - The Journals of Gerontology: Series …, 2019 - academic.oup.com
The rise in human longevity is one of humanity's crowning achievements. Although
advances in public health beginning in the 19th century initiated the rise in life expectancy …

[图书][B] Prospective longevity: A new vision of population aging

WC Sanderson, S Scherbov - 2019 - books.google.com
From two leading experts, a revolutionary new way to think about and measure aging. Aging
is a complex phenomenon. We usually think of chronological age as a benchmark, but it is …

The challenges of human population ageing

M Sander, B Oxlund, A Jespersen, A Krasnik… - Age and …, 2015 - academic.oup.com
The 20th century saw an unprecedented increase in average human lifespan as well as a
rapid decline in human fertility in many countries of the world. The accompanying worldwide …

Quantification of biological aging in young adults

DW Belsky, A Caspi, R Houts… - Proceedings of the …, 2015 - National Acad Sciences
Antiaging therapies show promise in model organism research. Translation to humans is
needed to address the challenges of an aging global population. Interventions to slow …

The degree of frailty as a translational measure of health in aging

SE Howlett, AD Rutenberg, K Rockwood - Nature Aging, 2021 - nature.com
Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

Recent trends and increasing differences in life expectancy present opportunities for multidisciplinary research on aging

EM Crimmins - Nature Aging, 2021 - nature.com
Recent trends and increasing differences in life expectancy present opportunities for
multidisciplinary research on aging | Nature Aging Skip to main content Thank you for visiting …