[HTML][HTML] The role of histone modifications: from neurodevelopment to neurodiseases

J Park, K Lee, K Kim, SJ Yi - Signal Transduction and Targeted Therapy, 2022 - nature.com
Epigenetic regulatory mechanisms, including DNA methylation, histone modification,
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …

Epigenetic mechanisms in neurogenesis

B Yao, KM Christian, C He, P Jin, G Ming… - Nature reviews …, 2016 - nature.com
In the embryonic and adult brain, neural stem cells proliferate and give rise to neurons and
glia through highly regulated processes. Epigenetic mechanisms—including DNA and …

[HTML][HTML] Histone regulation in the CNS: basic principles of epigenetic plasticity

I Maze, KM Noh, CD Allis - Neuropsychopharmacology, 2013 - nature.com
Postmitotic neurons are subject to a vast array of environmental influences that require the
nuclear integration of intracellular signaling events to promote a wide variety of neuroplastic …

[PDF][PDF] Critical role of histone turnover in neuronal transcription and plasticity

I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras… - Neuron, 2015 - cell.com
Turnover and exchange of nucleosomal histones and their variants, a process long believed
to be static in post-replicative cells, remains largely unexplored in brain. Here, we describe a …

Epigenetic regulation in neurodegenerative diseases

A Berson, R Nativio, SL Berger, NM Bonini - Trends in neurosciences, 2018 - cell.com
Mechanisms of epigenetic regulation, including DNA methylation, chromatin remodeling,
and histone post-translational modifications, are involved in multiple aspects of neuronal …

Invited review: epigenetics in neurodevelopment

RD Salinas, DR Connolly… - … and applied neurobiology, 2020 - Wiley Online Library
Neural development requires the orchestration of dynamic changes in gene expression to
regulate cell fate decisions. This regulation is heavily influenced by epigenetics, heritable …

Epigenetic regulation of neurogenesis in the adult mammalian brain

J Sun, J Sun, G Ming, H Song - European Journal of …, 2011 - Wiley Online Library
Epigenetic regulation represents a fundamental mechanism to maintain cell‐type‐specific
gene expression during development and serves as an essential mediator to interface the …

Chromatin remodeling in neural development and plasticity

J Hsieh, FH Gage - Current opinion in cell biology, 2005 - Elsevier
Neural stem cells generate distinct cell types for tissue formation and cell replacement
during development and throughout adulthood. Neural development and plasticity are …

[HTML][HTML] Epigenetic regulation of neural gene expression and neuronal function

J Feng, S Fouse, G Fan - Pediatric research, 2007 - nature.com
The development and function of the CNS requires accurate gene transcription control in
response to proper environmental signals. Epigenetic mechanisms, including DNA …

The role of epigenetic mechanisms in the regulation of gene expression in the nervous system

J Cholewa-Waclaw, A Bird… - Journal of …, 2016 - Soc Neuroscience
Neuroepigenetics is a newly emerging field in neurobiology that addresses the epigenetic
mechanism of gene expression regulation in various postmitotic neurons, both over time and …