Aging-related salivary dysfunction commonly induces the poor oral health, including
decreased saliva flow and dental caries. Although the clinical significance of the salivary …

Aging-related salivary dysfunction typically causes reduced saliva volumes, which leads to
debilitating consequences, even affecting patient quality of life. Understanding the …

Metabolites in human biofluids reflect individual physiological states influenced by various
factors. Using liquid chromatography-mass spectrometry (LC–MS), we conducted non …

This review describes an approach to examining the interaction of aging and systemic
disease on a key aspect of oral physiology, salivation. The approach requires several steps …

The salivary proteome consists of thousands of proteins, which include, among others,
hormonal modulators of energy intake and output. Although the functions of this prominent …

Xerostomia is a major complaint of many elderly individuals, and although they seek
medical help, it usually provides no adequate relief. This complaint is considered a major …

Abstract Background and Objectives Salivary glands in the elderly commonly exhibit salivary
dysfunction resulting dry mouth, poor oral hygiene, and dental caries. However, in vivo …

Although the physiological control of salivary secretion has been well studied, the impact of
disease on salivary gland function and how this changes the composition and function of …

The proteome of whole saliva, in contrast to that of serum, is highly susceptible to a variety of
physiological and biochemical processes. First, salivary protein secretion is under …

Saliva is crucial to oral processing of food and consequently is also related to the sensory
and textural experience. It is often assumed that the secretion and properties of saliva …