Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.

NL Colich, ML Rosen, ES Williams… - Psychological …, 2020 - psycnet.apa.org
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …

Early experiences of threat, but not deprivation, are associated with accelerated biological aging in children and adolescents

JA Sumner, NL Colich, M Uddin, D Armstrong… - Biological …, 2019 - Elsevier
Background Recent conceptual models argue that early life adversity (ELA) accelerates
development, which may contribute to poor mental and physical health outcomes. Evidence …

Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood

EJ Hamlat, AA Prather, S Horvath… - Developmental …, 2021 - Wiley Online Library
Background Given associations linking early life adversity, pubertal timing, and biological
aging, we examined the direct and indirect effects of early life trauma on adult biological …

Early-life adversity accelerates child and adolescent development

J Belsky - Current Directions in Psychological Science, 2019 - journals.sagepub.com
Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …

Early life adversity and adult biological risk profiles

EM Friedman, AS Karlamangla… - Psychosomatic …, 2015 - journals.lww.com
Objectives To determine whether there is a relationship between early life adversity (ELA)
and biological parameters known to predict health risks and to examine the extent to which …

Neurostructural traces of early life adversities: A meta-analysis exploring age-and adversity-specific effects

TM Pollok, A Kaiser, EJ Kraaijenvanger… - Neuroscience & …, 2022 - Elsevier
Early life adversities (ELAs) are associated with an increased risk of psychopathology, with
studies suggesting a relation to structural brain alterations. Given the recently growing …

The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)

D Joshi, A Gonzalez, D Lin, P Raina - Aging Cell, 2023 - Wiley Online Library
Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …

Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation

JG Miller, TC Ho, KL Humphreys, LS King… - Cerebral …, 2020 - academic.oup.com
Early life stress (ELS) may accelerate frontoamygdala development related to
socioemotional processing, serving as a potential source of resilience. Whether this circuit is …

[HTML][HTML] The effects of early life adversity on children's mental health and cognitive functioning

M Wade, L Wright, KE Finegold - Translational Psychiatry, 2022 - nature.com
Emerging evidence suggests that partially distinct mechanisms may underlie the association
between different dimensions of early life adversity (ELA) and psychopathology in children …

Neurobiological markers of resilience to early-life adversity during adolescence

ASM Leal, JA Silvers - Biological Psychiatry: Cognitive Neuroscience and …, 2021 - Elsevier
Early-life adversity (ELA) exposure (eg, trauma, abuse, neglect, or institutional care) is a
precursor to poor physical and mental health outcomes and is implicated in 30% of adult …