Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion

KX Yu, WJ Yuan, HZ Wang, YX Li - Cancer Immunology, Immunotherapy, 2024 - Springer
In the malignant progression of tumors, there is deposition and cross-linking of collagen, as
well as an increase in hyaluronic acid content, which can lead to an increase in extracellular …

Mechanobiology of Adipocytes

SP Blade, DJ Falkowski, SN Bachand, SJ Pagano… - Biology, 2024 - mdpi.com
Simple Summary The rising population of people with obesity has presented an important
need for the study of how adipocytes (fat cells) behave and affect biological function …

[HTML][HTML] Suv39h1: Targeting epigenetics to treat liver fibrosis

KA Papavassiliou, AG Papavassiliou - Journal of Cellular and …, 2024 - ncbi.nlm.nih.gov
A recent study published in Gut by Kong et al. revealed that a suppressor of variegation 3–9
homologue 1 (Suv39h1)-driven epigenetic mechanism is involved in the regulation of …

Cell recognition based on features extracted by AFM and parameter optimization classifiers

J Wang, F Yang, B Wang, J Hu, M Liu, X Wang… - Analytical …, 2024 - pubs.rsc.org
Intelligent technology can assist in the diagnosis and treatment of disease, which would
pave the way towards precision medicine in the coming decade. As a key focus of medical …

[HTML][HTML] Are YAP and TAZ valid prognostic signatures for NSCLC patients?

AN Gargalionis, KA Papavassiliou… - Journal of Cellular and …, 2024 - ncbi.nlm.nih.gov
To the Editor, It is well established that cancer cell biomechanics represents an important
factor engaged in non-small cell lung cancer (NSCLC) development and progression …

P–cadherin mechanoactivates tumor–mesothelium metabolic coupling to promote ovarian cancer metastasis

J Ma, SKY To, KSW Fung, K Wang, J Zhang… - bioRxiv, 2024 - biorxiv.org
Peritoneal metastasis exacerbates the prognosis of ovarian cancer patients. Adhesion of
cancer cells to mesothelium is a rate-limiting prerequisite for this process. How metastatic …

[PDF][PDF] BIOMECHANICS OF CANCER CELL MOTILITY

A Isomursu - utupub.fi
Metastatic cancer is a devastating disease and an unmet clinical need. The local invasion
and colonization of distant organs by cancer cells are both dependent on cell migration, a …