A mammalian methylation array for profiling methylation levels at conserved sequences

A Arneson, A Haghani, MJ Thompson… - Nature …, 2022 - nature.com
Infinium methylation arrays are not available for the vast majority of non-human mammals.
Moreover, even if species-specific arrays were available, probe differences between them …

[PDF][PDF] A simple guide to de novo transcriptome assembly and annotation

V Raghavan, L Kraft, F Mesny… - Briefings in …, 2022 - academic.oup.com
A transcriptome constructed from short-read RNA sequencing (RNA-seq) is an easily
attainable proxy catalog of protein-coding genes when genome assembly is unnecessary …

Taming transposable elements in vertebrates: from epigenetic silencing to domestication

MV Almeida, G Vernaz, ALK Putman, EA Miska - Trends in Genetics, 2022 - cell.com
Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …

African lungfish genome sheds light on the vertebrate water-to-land transition

K Wang, J Wang, C Zhu, L Yang, Y Ren, J Ruan, G Fan… - Cell, 2021 - cell.com
Lungfishes are the closest extant relatives of tetrapods and preserve ancestral traits linked
with the water-to-land transition. However, their huge genome sizes have hindered …

Contrasting signatures of genomic divergence during sympatric speciation

AF Kautt, CF Kratochwil, A Nater… - Nature, 2020 - nature.com
The transition from 'well-marked varieties' of a single species into 'well-defined species'—
especially in the absence of geographic barriers to gene flow (sympatric speciation)—has …

Six reference-quality genomes reveal evolution of bat adaptations

D Jebb, Z Huang, M Pippel, GM Hughes… - Nature, 2020 - nature.com
Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity
and unique immunity. High-quality genomes are crucial for understanding the molecular …

ExpressAnalyst: A unified platform for RNA-sequencing analysis in non-model species

P Liu, J Ewald, Z Pang, E Legrand, YS Jeon… - Nature …, 2023 - nature.com
The increasing application of RNA sequencing to study non-model species demands easy-
to-use and efficient bioinformatics tools to help researchers quickly uncover biological and …

The information theory of aging

YR Lu, X Tian, DA Sinclair - Nature aging, 2023 - nature.com
Abstract Information storage and retrieval is essential for all life. In biology, information is
primarily stored in two distinct ways: the genome, comprising nucleic acids, acts as a …

The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

C Shao, S Sun, K Liu, J Wang, S Li, Q Liu, BE Deagle… - Cell, 2023 - cell.com
Antarctic krill (Euphausia superba) is Earth's most abundant wild animal, and its enormous
biomass is vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome …

[HTML][HTML] Rethinking fish biology and biotechnologies in the challenge era for burgeoning genome resources and strengthening food security

JF Gui, L Zhou, XY Li - Water Biology and Security, 2022 - Elsevier
Fish biology has been developed for more than 100 years, but some important
breakthroughs have been made in the last decade. Early studies commonly concentrated on …