Intracranial Hemorrhage During Dual Antiplatelet Therapy: JACC Review Topic of the Week

ACT Ha, DL Bhatt, JT Rutka, SC Johnston… - Journal of the American …, 2021 - jacc.org
Dual antiplatelet therapy (DAPT) with acetylsalicylic acid and a P2Y12 inhibitor is an
established therapy for a broad spectrum of patients with cardiovascular disease. The …

[HTML][HTML] Revascularization and medical therapy for chronic coronary syndromes: lessons learnt from recent trials, a literature review

V Pham, A Moroni, E Gall, A Benedetti… - Journal of Clinical …, 2023 - mdpi.com
Stable coronary artery disease (CAD) has recently been replaced by a new entity described
as chronic coronary syndrome (CCS). This new entity has been developed based on a …

Rivaroxaban plus aspirin versus aspirin alone in patients with prior percutaneous coronary intervention (COMPASS-PCI)

KR Bainey, RC Welsh, SJ Connolly, T Marsden… - Circulation, 2020 - Am Heart Assoc
Background: The COMPASS trial (Cardiovascular Outcomes for People using
Anticoagulation Strategies) demonstrated that dual pathway inhibition (DPI) with …

Ticagrelor: clinical development and future potential

NC Sanderson, WAE Parker… - Reviews in …, 2021 - eprints.whiterose.ac.uk
Platelets participate centrally in atherothrombosis, resulting in vessel occlusion and
ischaemia. Consequently, optimisation of antiplatelet regimens has the potential to further …

Personalised antiplatelet therapies for coronary artery disease: what the future holds

D Capodanno, DJ Angiolillo - European Heart Journal, 2023 - academic.oup.com
Coronary artery disease (CAD) is one of the leading causes of death globally, and
antiplatelet therapy is crucial for both its prevention and treatment. Antiplatelet drugs such as …

Bentracimab for ticagrelor reversal in patients undergoing urgent surgery

DL Bhatt, CV Pollack, CD Mazer, DJ Angiolillo… - NEJM …, 2022 - evidence.nejm.org
Background Ticagrelor is a reversible oral P2Y12 platelet inhibitor used to treat patients with
acute coronary syndromes, prior myocardial infarction, high-risk coronary artery disease …

Antithrombotic therapy for atherosclerotic cardiovascular disease risk mitigation in patients with coronary artery disease and diabetes mellitus

D Capodanno, DJ Angiolillo - Circulation, 2020 - Am Heart Assoc
Patients with diabetes mellitus (DM) are characterized by enhanced thrombotic risk
attributed to multiple mechanisms including hyperreactive platelets, hypercoagulable status …

Patient-tailored antithrombotic therapy following percutaneous coronary intervention

NMR van der Sangen, R Rozemeijer… - European heart …, 2021 - academic.oup.com
Dual antiplatelet therapy has long been the standard of care in preventing coronary and
cerebrovascular thrombotic events in patients with chronic coronary syndrome and acute …

[HTML][HTML] Dual antiplatelet therapy in coronary artery disease

R Sharma, P Kumar, SP Prashanth, Y Belagali - Cardiology and therapy, 2020 - Springer
Acute coronary syndrome (ACS) is principally driven by platelet aggregation. Dual
antiplatelet therapy (DAPT) has demonstrated a reduction in recurrent ischemic events. The …

[HTML][HTML] Management of residual risk in chronic coronary syndromes. Clinical pathways for a quality-based secondary prevention

S Giubilato, F Lucà, MG Abrignani, L Gatto… - Journal of Clinical …, 2023 - mdpi.com
Chronic coronary syndrome (CCS), which encompasses a broad spectrum of clinical
presentations of coronary artery disease (CAD), is the leading cause of morbidity and …