Cancers represent complex ecosystems comprising tumor cells and a multitude of non-
cancerous cells, embedded in an altered extracellular matrix. The tumor microenvironment …

Most cancer-associated deaths occur due to metastasis, yet our understanding of metastasis
as an evolving, heterogeneous, systemic disease and of how to effectively treat it is still …

Organ-specific metastasis is the primary cause of cancer patient death. The distant
metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of …

Abstract Treatment of metastatic cancer is one of the biggest challenges in anticancer
therapy. Curcumin is interesting nature polyphenolic compound with unique biological and …

Luminal breast cancers are hormone receptor (estrogen and/or progesterone) positive that
are further divided into HER2-negative luminal A and HER2-positive luminal B subtypes …

Cancer cell invasion, intravasation and survival in the bloodstream are early steps of the
metastatic process, pivotal to enabling the spread of cancer to distant tissues. Circulating …

Over the past decade, novel methods for enrichment and identification of cancer cells
circulating in the blood have been established. Blood-based detection of cancer cells and …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

The efficient capture and detection of circulating tumor cells (CTCs) in blood is very
important for the early detection of cancer. In this work, efficient detection of CTCs through …

The separation and analysis of circulating tumor cells (CTCs) in liquid biopsy significantly
facilitated clinical cancer diagnosis and personalized therapy. However, current methods …