The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Mitochondria are organelles that are able to adjust and respond to different stressors and
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …

Cells and tissues generate and are exposed to various mechanical forces that act across a
range of scales, from tissues to cells to organelles. Forces provide crucial signals to inform …

Actin plays many well-known roles in cells, and understanding any specific role is often
confounded by the overlap of multiple actin-based structures in space and time. Here, we …

Gastric cancer (GC) represents a significant burden of cancer-related mortality worldwide,
underscoring an urgent need for the development of early detection strategies and precise …

Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase
(AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3 …

The mechanisms by which cells sense their mechanical environment and transduce the
signal through focal adhesions and signaling pathways to the nucleus is an area of key …

Chemo‐immunotherapy has shown great success in boosting systemic anti‐tumor effects in
the clinic. However, cancer cells can escape the maximum impact of chemotherapy through …

Mechanobiology studies the mechanisms by which cells sense and respond to physical
forces, and the role of these forces in shaping cells and tissues themselves …

The tumor microenvironment (TME) play critical roles in tumor survival, progression, and
metastasis and can be considered potential targets for molecular imaging of cancer. The …