Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

Tumors are comprised of both cancer cells and surrounding stromal components. As an
essential part of the tumor microenvironment, the tumor stroma is highly dynamic …

Background Pancreatic cancer continues to be one of the world's most lethal cancers.
Chemotherapy resistance in patients with advanced pancreatic cancer often accompany …

Breast cancer is a heterogeneous disease with variable survival outcomes. Pathologists
grade the microscopic appearance of breast tissue using the Nottingham criteria, which are …

Spatially resolved transcriptomics provides genetic information in space toward elucidation
of the spatial architecture in intact organs and the spatially resolved cell-cell …

Stromal heterogeneity of tumor microenvironment (TME) plays a crucial role in malignancy
and therapeutic resistance. Cancer-associated fibroblasts (CAFs) are one of the major …

Podoplanin (PDPN) is a cell-surface mucin-like glycoprotein that plays a critical role in tumor
development and normal development of the lung, kidney, and lymphatic vascular systems …

The biological complexity of cancer represents a tremendous clinical challenge, resulting in
the frequent failure of current treatment protocols. In the rapidly evolving scenario of a …

Nanoceria or cerium oxide nanoparticles characterised by the co-existing of Ce3+ and Ce4+
that allows self-regenerative, redox-responsive dual-catalytic activities, have attracted …

Polyphenols are secondary metabolites produced by plants, which contribute to the plant's
defense against abiotic stress conditions (eg, UV radiation and precipitation), the aggression …