Cancer metabolic alterations have been emphasized to protect cancer cells from cell death.
The metabolic reprogramming toward a mesenchymal state makes cancer cells resistant to …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Epithelial cells acquire mesenchymal phenotypes through epithelial‐mesenchymal
transition (EMT) during cancer progression. However, how epithelial cells retain their …

Mounting evidence supports the idea that transcriptional patterns serve as more specific
identifiers of active enhancers than histone marks; however, the optimal strategy to identify …

We outline a phenomenological theory of evolution and origin of life by combining the
formalism of classical thermodynamics with a statistical description of learning. The …

The birth of long non-coding RNAs (lncRNAs) is closely associated with the presence and
activation of repetitive elements in the genome. The transcription of endogenous …

Background Resistance to temozolomide (TMZ) is a major obstacle to preventing
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …

Abstract Stanniocalcin 2 (STC2) is a glycoprotein which is expressed in a broad spectrum of
tumour cells and tumour tissues derived from human breast, colorectum, stomach …

Fusion RNAs are a hallmark of some cancers. They result either from chromosomal
rearrangements or from splicing mechanisms that are non-chromosomal rearrangements …

Nonadaptive hypotheses on the evolution of eukaryotic genome size predict an expansion
when the process of purifying selection becomes weak. Accordingly, species with huge …