Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …

The ferritin nanocage is an endogenous protein that exists in almost all mammals. Its hollow
spherical structure that naturally stores iron ions has been diversely exploited by …

Despite remarkable advances over the past several decades, many therapeutic
nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity …

The rising incidence and persistent thrombosis in multiple cancers including those that are
immunosuppressive highlight the need for understanding the tumor coagulome system and …

Background Ferritin, a ubiquitously distributed iron storage protein, can specifically target
tumor cells through transferrin receptor 1. Due to its rearrangeable nanocage structure …

The inadequate tumor accumulation of anti-cancer agents is a major shortcoming of current
therapeutic drugs and remains an even more significant concern in the clinical prospects for …

Nanoparticles (NPs) have been widely used as target delivery vehicles for therapeutic
goods; however, compared with inorganic and organic nanomaterials, protein …

Ferritin is an endogenous protein which is self-assembled by 24 subunits into a highly
uniform nanocage structure. Due to the drug-encapsulating ability in the hollow inner cavity …

Programming protein nanomaterials to respond to changes in environmental conditions is a
current challenge for protein design and is important for targeted delivery of biologics. Here …

The extracellular matrix (ECM) has been strongly correlated with cancer progression in
various tumor types. However, the specific mechanisms underlying ECM-associated tumor …