Natural killer (NK) cells are innate immune lymphocytes that recognize and kill cancer and
infected cells, which makes them unique 'off-the-shelf'candidates for a new generation of …

Cell function relies on the spatiotemporal dynamics of metabolic reactions. In all
physiopathological processes of tissues, mechanical forces impact the structure and function …

Despite the fact that different genetic programmes drive metastasis of solid tumours, the
ultimate outcome is the same: tumour cells are empowered to pass a series of physical …

Extracellular vesicles have undergone a paradigm shift from being considered as 'waste
bags' to being central mediators of cell-to-cell signaling in homeostasis and several …

Chemotherapy is a conventional cancer treatment in clinical settings. Although numerous
nano drug delivery systems have been developed, the chemotherapeutic effect is greatly …

Glioma progression is accompanied with increased tumor tissue stiffness, yet the underlying
mechanisms are unclear. Herein, we employed atomic force microscopy analysis to show …

Mechanical cues play a crucial role in regulating physiological and pathological processes,
and atomic force microscopy (AFM) has become an important and standard tool for …

With the application of high throughput sequencing technologies at single-cell resolution,
studies of the tumor microenvironment in glioblastoma, one of the most aggressive and …

The stiffness of tumors and their host tissues is much higher than most hydrogels, which are
conventionally used to study in vitro cancer progression. The tumoroid assay is an …

Despite many advances in cancer treatment, cancer still remains a major global health
problem owing to its high rate of recurrence, the tendency to metastasize, and the …