Tumor tissue engineering holds great promise for replicating the physiological and
behavioral characteristics of tumors in vitro. Advances in this field have led to new …

Vascular pericytes, important mural cells that retain progenitor cell properties and protect
vascular integrity in healthy tissues, are often associated with tumor development, but their …

As one of important components of tumor microenvironment, CAFs (cancer-associated
fibroblasts) play a vital role in the development and metastasis of bladder cancer. The …

The actin cytoskeleton is a dynamic network that regulates cellular behavior from
development to disease. By rearranging the actin cytoskeleton, cells are capable of …

During metastasis, tumor cells need to adapt to their dynamic microenvironment and modify
their mechanical properties in response to both chemical and mechanical stimulation …

The characteristics and fate of cancer cells partly depend on their environmental stiffness, ie,
the local mechanical cues they face. HepaRG progenitors are liver carcinoma cells …

It is well known that both fluid mechanics and matrix stiffness present within the cellular
microenvironments play an essential role in the physiological and pathological processes of …

Photodynamic therapy (PDT) is frequently used in cancer treatment in clinical settings.
However, its applications in stroma-rich solid tumors, eg, triple negative breast cancer, are …

Mechanical forces are the indispensable constituent of environmental cues, such as gravity,
barometric pressure, vibration, and contact with bodies, which are involved in pattern and …

Yes-associated protein (YAP) is an essential driver of hepatocellular carcinoma (HCC)
progression and the ubiquitin-proteasome system controls its abundance. However, the role …